| VPI-7分子筛的合成及生物学性能 |
| |
| 引用本文： | 李瑞延,王双,李冬冬,秦彦国,于吉红.VPI-7分子筛的合成及生物学性能[J].高等学校化学学报,2017,38(11). |
| |
| 作者姓名： | 李瑞延 王双 李冬冬 秦彦国 于吉红 |
| |
| 作者单位： | 1. 吉林大学第二医院,长春,130041;2. 吉林大学化学学院,长春,130012;3. 吉林大学材料科学与工程学院,长春,130012 |
| |
| 基金项目： | 国家自然科学基金，吉林省省级产业专业创新专项资金，吉林省科技发展计划项目(批准号:20150414006GH)资助.Supported by the National Natural Science Foundation of China，the Special Fund Project of Jilin Provincial Industrial Innovation |
| |
| 摘 要： | 采用水热法,通过调变反应溶胶的量合成了不同尺寸的不规则圆片状多孔锌硅分子筛VPI-7,并研究了其生物学性能.扫描电子显微镜观测结果表明,制备的样本由VPI-7条状晶体聚集成微球,并进一步相互交联形成微米级孔隙,其形貌可以促进钙磷化合物在样品表面的沉积,同时可以负载并缓释蛋白.细胞学检测结果表明,VPI-7分子筛有利于细胞黏附增殖,具有良好的生物相容性.
|
| 关 键 词： | 锌硅分子筛VPI-7 生物相容性 负载并缓释蛋白 |
Synthesis and Biological Evaluation of VPI-7 Zeolite |
| |
| LI Ruiyan,WANG Shuang,LI Dongdong,QIN Yanguo,YU Jihong.Synthesis and Biological Evaluation of VPI-7 Zeolite[J].Chemical Research In Chinese Universities,2017,38(11). |
| |
| Authors: | LI Ruiyan WANG Shuang LI Dongdong QIN Yanguo YU Jihong |
| |
| Abstract: | Porous zincosilicate zeolite, VPI-7, was synthesized through hydrothermal approach, and the size of samples were adjusted by varying amounts of sol. Also, the biological properties of the samples were charactered. The characteristic results showed that the prepared samples were aggregated into microspheres by VPI-7 rod-shaped crystals, and the crystals further cross-linked and formed numerous micron-sized pores, which provided good morphological features for their biological properties. In addition, the surface topography for VPI-7 had the ability to promote the deposition of calcium phosphate, and load/release protein. The in vitro experiments suggested that VPI-7 was conducive to cell adhesion and proliferation, with good biocompatibility. VPI-7 showed excellent biological properties, and has potential to be applied as implant used in bone repair and replacement. |
| |
| Keywords: | Zincosilicate zeolite VPI-7 Biocompatibility Load/release protein |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
