| 脂肪干细胞在眼科的应用及研究进展 |
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| 引用本文： | 李宏松,邹俊. 脂肪干细胞在眼科的应用及研究进展[J]. 国际眼科杂志, 2013, 13(11): 2233-2236 |
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| 作者姓名： | 李宏松 邹俊 |
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| 作者单位： | 中国上海市,上海交通大学附属第六人民医院眼科;中国上海市,上海交通大学附属第六人民医院眼科 |
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| 摘 要： | 脂肪干细胞(adipose-derived stem cells,ADSCs)是存在于脂肪组织的间充质干细胞,具有多向分化潜能,在特定的条件下可以分化为脂肪细胞、成骨细胞、成软骨细胞等中胚层细胞,甚至可以跨胚层分化为神经细胞等外胚层细胞及肝细胞等内胚层细胞。ADSCs还有易于获取、对取材区损伤小等众多优势,使其成为组织修复等领域的热点之一。本文对ADSCs的生物学特性及其在眼科领域的研究进行了分类总结,以期为ADSCs在眼科的应用研究给予有益的提示。
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| 关 键 词： | 脂肪干细胞 角膜 视网膜 诱导分化 眼科 |
| 收稿时间： | 2013-08-19 |
| 修稿时间： | 2013-10-14 |
Development and application of adipose-derived stem cells in ophthalmology |
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| Hong-Song Li and Jun Zou. Development and application of adipose-derived stem cells in ophthalmology[J]. International Eye Science, 2013, 13(11): 2233-2236 |
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| Authors: | Hong-Song Li and Jun Zou |
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| Affiliation: | Department of Ophthalmology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200233, China;Department of Ophthalmology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200233, China |
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| Abstract: | Adipose-derived stem cells(ADSCs)are multipotent population of cells with multipotential differentiation capability, which can differentiate into mesoderm including adipocyte osteoblasts and chondroblasts in specific conditions, even the endoderm cells like hepatocyte and and ectoderm cells like neurocyte. Besides, ADSC has many advantages like easy access and light damage to selected area, which enables it to become a hotspot in tissue repair area. This paper made a classified summary on the biological characteristics of corneal epithelium and its application in research to offer beneficial hints to the research of ADSC application in ophthalmology. |
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| Keywords: | adipose-derived stem cells cornea retina induced differentiation ophthalmology |
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