简析GLP与药物毒理学的关系

非临床研究质量管理规范（good laboratory practice for nonclinical study,GLP）是药物非临床安全性评价研究机构必须遵循的规范,与药物毒理学有着密切的联系。药物毒理学研究促进了GLP的发生与发展;同时,GLP要求实验管理做到规范化和标准化,保障了药物非临床安全性评价研究的科学性与可靠性,加快了我国药物毒理学研究与国际接轨。现就GLP与药物毒理学的关系进行简要的论述。

Relationship between GLP and drug toxicology

Good laboratory practice（GLP） for nonclinical study is a norm that must be followed by non-clinical drug safety evaluation agencies,and has a close relationship with drug toxicology.Drug toxicology promotes the occurrence and development of GLP.At the same time,GLP requires laboratory management to be normalized and standardized,which ensures the scientificity and reliability of nonclinical safety evaluation,and accelerates the internationalization of drug toxicology.In this paper,the relationship between GLP and drug toxicology is discussed.