| 青蒿素及其衍生物免疫抑制作用在防治葡萄膜炎中的前景 |
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| 引用本文： | 孙晓茹,毕宏生,郭俊国.青蒿素及其衍生物免疫抑制作用在防治葡萄膜炎中的前景[J].国际眼科杂志,2012,12(6):1078-1080. |
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| 作者姓名： | 孙晓茹 毕宏生 郭俊国 |
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| 作者单位： | 1. 山东中医药大学第一临床学院,中国山东省济南市,250355
2. 山东中医药大学附属眼科医院,山东中医药大学眼科研究所,中国山东省济南市,250002 |
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| 基金项目： | 国家自然科学基金资助项目（No.81072961） |
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| 摘 要： | 青篙素是从中药青篙中提取的药物，经化学改造可生成多种衍生物，随着对青蒿素及其衍生物药理作用的不断研究深入，发现其还具有较强的免疫抑制作用。鉴于青蒿素及其衍生物的临床应用和葡萄膜炎的免疫发病机制，青蒿素及其衍生物应用于葡萄膜炎前景十分广阔。
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| 关 键 词： | 葡萄膜炎 青蒿素 免疫抑制 |
| 收稿时间： | 2012/2/13 0:00:00 |
| 修稿时间： | 2012/4/17 0:00:00 |
Prospect of immunosuppression of Artemisinin and its derivatives in uveitis control |
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| Xiao-Ru Sun,Hong-Sheng Bi and Jun-Guo Guo.Prospect of immunosuppression of Artemisinin and its derivatives in uveitis control[J].International Journal of Ophthalmology,2012,12(6):1078-1080. |
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| Authors: | Xiao-Ru Sun Hong-Sheng Bi and Jun-Guo Guo |
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| Affiliation: | the First Clinical College of Shandong University of Traditional Chinese Medicine, Jinan 250355, Shandong Province, China;;the Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine,Eye Institute of Shandong University of Traditional Chinese Medicine,Jinan 250002,Shandong Province,China;the Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine,Eye Institute of Shandong University of Traditional Chinese Medicine,Jinan 250002,Shandong Province,China |
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| Abstract: | Artemisinin is extracted from herbal medicine,Artemisia annua L,which can be made into many derivatives after chemical alteration.With further research into the pharmacological effects of artemisinin and its derivatives,immunosuppression effect was discovered.Considering the clinical application of artemisinin and its derivatives,the prospect of immunosuppression effect in uveitis control is very promising. |
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| Keywords: | uveitis artemisinin immunosuppression |
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