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RBF网络光度法与BP网络光度法的比较
引用本文:方洪壮,吴刚,孙长海.RBF网络光度法与BP网络光度法的比较[J].计算机与应用化学,2002,19(4):415-418.
作者姓名:方洪壮  吴刚  孙长海
作者单位:佳木斯大学药物分析教研室,黑龙江,佳木斯,154003
摘    要:目的:探讨神经网络光度法用于复方制剂的含量测定。方法:训练集为按L25(5^6)正交表制备的25组标准混合液的吸光度数据和各组分的浓度数据,混合液中各组分的5个浓度水平分别为80%、90%、100%,110%和120%。预报集采用复方制剂的吸光度数据。网络的输入为混合物的吸光度,网络的输出为各组分的浓度。分别用径向基函数网络和Levenberg-Marqurdt优化算法的BP网络处理数据。结果:复方阿司匹林片和联磺甲氧苄啶片的紫外分光光度法测定结果表明,径向基函数网络在网络训练时间和测定精度等方面好于Levenberg-Marqurdt优化算法的BP网络。结论:径向基函数网络光度法测定复方制剂简便,准确。

关 键 词:RBF网络光度法  BP网络光度法  径向基函数网络  复方制剂  紫外分光光度法  含量测定  阿司匹林  联磺甲氧苄啶
文章编号:1001-4160(2002)04-415-418
修稿时间:2001年7月10日

Comparision Between RBF Network Spectrophotometry and BP Network Spectrophotometry
FANG Hong-zhuang,WU Gang,SUN Chang-hai.Comparision Between RBF Network Spectrophotometry and BP Network Spectrophotometry[J].Computers and Applied Chemistry,2002,19(4):415-418.
Authors:FANG Hong-zhuang  WU Gang  SUN Chang-hai
Abstract:To delve neural network spectrophotometry appling to content determination of compound preparation. The train set was consisted of data of 25 group standard mixtrue which prepared according to orthogonal layout. The predict set was obsorbance data of compound preparation. The input of network was mixture obsorbance and the output was component concentration. The ab-sorbance data of three component compound preparation was processed with radial basis function network and BP network of Leven-berg-Marqurdt optimazation algorithm, respectively. Compound aspirin tablets and tablets of sulfamethoxazole sulfadiazine and trimethoprim have been determined by UV spectrophotometry. The results obtained with radial basis function network are better than those provided with the BP network in traing time and precision of determination. The radial basis function network spectrophotometry is simple and accuracy in the determination of compound preparation.
Keywords:radial basis network  BP network  algorithm of levenberg-marquardt optimization  compound preparation  UV spec-trophotometry  content determination
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