胸膜孤立性纤维瘤6例报告并文献复习

目的探讨胸膜孤立性纤维瘤（SFTP）的诊断和外科治疗。方法回顾分析河南大学淮河医院胸外科1990-01-2009-08间收治的胸膜孤立性纤维瘤6例的临床资料。结果胸闷、胸痛、咳嗽、咯痰、发热是SFTP的主要症状。诊断主要依据免疫组化分析,所有患者的CD34、vi mentin、bcl-2和CD99均阳性表达。随访5个月至19 a,无复发及转移。结论胸膜孤立性纤维瘤的诊断主要依[靠免疫组化分析,根治性切除是主要治疗手段。

Solitary Fibrous Tumor of Pleura :6 Cases Report and Literature Review

Objective To explore the dignosis and treatment of solitary fibrous tumor of pleura（SFTP）.Methods A retrospective review of the clinical records of 6 patients who had undergone surgical resection for solitary fibrous tumors of pleura during a 19 year period（1990-2009） was conducted.Results Chest distressc、chest pain 、cough 、stethocatharsis and heat were common symptoms of SFTP at the time of diagnosis.Immunohistochemical analysis revealed positivity for CD34、vimentin、bcl-2 and CD99 in all tumors.Follow up periods ranged from 5 to 236 months,all patients had remained well with no metastasis,and local recurrence occurred.Conclusions Diagnosis of SFTPs relies on a thorough immunopathologic examination of the resected tumor.Complete resection is the mainstay of cure.