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Influence of inhomogeneous static magnetic field-exposure on patients with erosive gastritis: a randomized,self- and placebo-controlled,double-blind,single centre,pilot study
Authors:Márk Juhász  Viktor L. Nagy  Hajnal Székely  Dorottya Kocsis  Zsolt Tulassay  János F. László
Affiliation:1.2nd Department of Internal Medicine, Semmelweis University, Budapest, Szentkirályi u. 46, 1088, Hungary;2.e-Comers LLC, Csejtei u. 1-3, Budapest 1025, Hungary;3.Department of Computer Science, University of Debrecen, Kassai út 26, Debrecen 4028, Hungary
Abstract:This pilot study was devoted to the effect of static magnetic field (SMF)-exposure on erosive gastritis. The randomized, self- and placebo-controlled, double-blind, pilot study included 16 patients of the 2nd Department of Internal Medicine, Semmelweis University diagnosed with erosive gastritis. The instrumental analysis followed a qualitative (pre-intervention) assessment of the symptoms by the patient: lower heartburn (in the ventricle), upper heartburn (in the oesophagus), epigastric pain, regurgitation, bloating and dry cough. Medical diagnosis included a double-line upper panendoscopy followed by 30 min local inhomogeneous SMF-exposure intervention at the lower sternal region over the stomach with peak-to-peak magnetic induction of 3 mT and 30 mT m−1 gradient at the target site. A qualitative (post-intervention) assessment of the same symptoms closed the examination. Sham- or SMF-exposure was used in a double-blind manner. The authors succeeded in justifying the clinically and statistically significant beneficial effect of the SMF- over sham-exposure on the symptoms of erosive gastritis, the average effect of inhibition was 56% by p = 0.001, n = 42 + 96. This pilot study was aimed to encourage gastroenterologists to test local, inhomogeneous SMF-exposure on erosive gastritis patients, so this intervention may become an evidence-based alternative or complementary method in the clinical use especially in cases when conventional therapy options are contraindicated.
Keywords:erosive gastritis   randomized   self- and placebo-controlled   double-blind   pilot study   static magnetic field-exposure
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