|
|||||
|
|
Sodium channel mutations (T929I and F1534S) found in pyrethroid-resistant strains of the cigarette beetle,Lasioderma serricorne (Coleoptera: Anobiidae) |
|
| Authors: | Naoto Fukazawa Ryota Takahashi Hinako Matsuda Yuya Mikawa Toshiyuki Suzuki Tomohiro Suzuki Shoji Sonoda |
| Affiliation: | 1.Leaf Tobacco Research Center, Japan Tobacco Inc., Oyama, Tochigi 323–0808, Japan;2.School of Agriculture, Utsunomiya University, Utsunomiya, Tochigi 321–8505, Japan;3.Center for Bioscience Research and Education, Utsunomiya University,Utsunomiya, Tochigi 321–8505, Japan |
| Abstract: | RNA-seq data analysis of cigarette beetle (Lasioderma serricorne) strains having different sensitivities to pyrethroids identified sodium channel mutations in strains showing pyrethroid resistance: the T929I and F1534S mutations. These results suggest that reduced sensitivity of the sodium channel confers the pyrethroid resistance of L. serricorne. Results also showed that the F1534S mutation mostly occurred concurrently with the T929I mutation. The functional relation between both mutations for pyrethroid resistance is discussed. |
| Keywords: | insecticide resistance PCR-RFLP stored products target insensitivity tobacco beetle |
