| 电针联合小剂量氯氮平治疗难治性精神分裂症的疗效观察 |
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| 引用本文： | 熊典樟,刘灵灵,易燕,叶锋.电针联合小剂量氯氮平治疗难治性精神分裂症的疗效观察[J].针刺研究,2010,35(2). |
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| 作者姓名： | 熊典樟 刘灵灵 易燕 叶锋 |
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| 作者单位： | 1. 江西省宜春市第三人民医院精神科,宜春,336000
2. 宜春市医药协会办公室,宜春,336000 |
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| 摘 要： | 目的:评价电针联合小剂量氯氮平治疗难治性精神分裂症的有效性和安全性。方法:将难治性精神分裂症患者随机分为西药组和针药结合组各40例。西药组患者均采用口服氯氮平治疗;针药结合组患者选百会及太阳穴电针治疗,同时口服小剂量氯氮平。比较两组患者治疗前后阳性与阴性症状量表(PAN-SS)、副反应量表(TESS)评分及临床疗效。结果:两组治疗后PANSS均下降,且两组比较差异无统计学意义(P>0.05)。治疗后针药结合组TESS评分结果显著低于西药组(P<0.01)。西药组愈显率35.0%(14/40),有效率77.5%(31/40),针药结合组愈显率32.5%(13/40),有效率72.5%(29/40),两组比较差异无统计学意义(P>0.05)。结论:两组方法治疗难治性精神分裂症疗效相当,而针药结合组不良反应更轻,提示电针配合小剂量氯氮平是治疗难治性精神分裂症的较好方法。
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| 关 键 词： | 难治性精神分裂症 电针疗法 氯氮平 阳性与阴性症状量表 副反应量表 |
Observation on the Therapeutic Effect of Electroacupuncture Combined with Small Dose of Clozapine in Clinical Treatment of Refractory Schizophrenia |
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| XIONG Dian-zhang,LIU Ling-ling,YI-Yan,YE-Feng.Observation on the Therapeutic Effect of Electroacupuncture Combined with Small Dose of Clozapine in Clinical Treatment of Refractory Schizophrenia[J].Acupuncture Research,2010,35(2). |
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| Authors: | XIONG Dian-zhang LIU Ling-ling YI-Yan YE-Feng |
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| Affiliation: | XIONG Dian-zhang,LIU Ling-ling1,YI-Yan,YE-Feng(The 3rd People's Hospital of Yichun,Yichun 336000,China,1The Medical Association of Yichun City,Yichun 336000) |
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| Abstract: | Objective To observe the effect of electroacupuncture(EA) in combination with small dose of clozapine on clinical symptoms of refractory schizophrenia patients so as to evaluate its validity and security.Methods Eighty schizophrenia patients were randomized into medication group and EA+medication group(n=40/group).Patients of medication group were treated with conventional oral administration of clozapine(50-100 mg/d to 200-500 mg/d,for 8 weeks) and those of EA+ medication group treated by EA of Baihui(GV 2... |
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| Keywords: | Refractory schizophrenia Electroacupuncture Clozapine PANSS score TESS score |
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