| pH指示剂吸收度比值法测定盐酸苯海拉明的含量 |
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| 引用本文： | 赵春杰,于治国,叶向东,杨忠斌.pH指示剂吸收度比值法测定盐酸苯海拉明的含量[J].沈阳药科大学学报,1992(1). |
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| 作者姓名： | 赵春杰 于治国 叶向东 杨忠斌 |
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| 作者单位： | 沈阳药学院药物分析教研室，沈阳药学院药物分析教研室，沈阳药学院药物分析教研室，沈阳市红旗制药厂研究所 |
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| 摘 要： | 本文报道pH指示剂吸收度比值法测定盐酸苯海拉明的含量。该法采用指示剂为0.05%麝香草酚蓝,测定波长440和603nm;标准液为0.1mol/L NaOH;仪器为WF-800D_2型分光光度计,UV-240型分光光度计.测得三批盐酸苯海拉明的含量分别为99.8,99.4和99.7%.同时与药典法比较,结果一致。
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| 关 键 词： | pH指示剂吸收度比值法 盐酸苯海拉明 |
QUANTITATIVE DETERMINATION OF DIPHENHYDRAMINE HYDROCHLORIDE BY pH INDICATOR ABSORBANCE RATIO METHOD |
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| Zhao Chunjie Yu Zhiguo Ye Xiangdong.QUANTITATIVE DETERMINATION OF DIPHENHYDRAMINE HYDROCHLORIDE BY pH INDICATOR ABSORBANCE RATIO METHOD[J].Journal of Shenyang Pharmaceutical University,1992(1). |
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| Authors: | Zhao Chunjie Yu Zhiguo Ye Xiangdong |
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| Affiliation: | Zhao Chunjie Yu Zhiguo Ye Xiangdong Department of Pharmaceutical Analysis,Shenyang Pharmacy College Yang Zhongbin Research Department,Hong Qi Pharmaceutical Factory |
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| Abstract: | In this study, diphenhydramine hydrochloride was determined quantitatively by pH indicator absorbance ratio method. The determination was carr- ied out easily, rapidly and accurately as follows:
Thymol blue and the standard solution of 0.1 mol/L NaOH were used; the absorbances at 440nm and 603nm were measured. The contents of three batches of diphenhydramine hydrochloride were 99.8%、99.4% and 99.7%, respectively. The method is comparable with the official quantitative analysis of diphenhydramine hydrochloride. |
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| Keywords: | The absorbance ratio method of pH indicator Diphenhydramine hydrochlorid |
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