| 辽宁省彰武县农村地区血清脂联素水平与脑卒中关系的病例对照研究 |
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| 引用本文： | 王灿,时景璞,付凌雨,王海龙,周波,李辉,腾文禹,董亚珞,董卫,富成国,王文利.辽宁省彰武县农村地区血清脂联素水平与脑卒中关系的病例对照研究[J].疾病控制杂志,2011(1):11-14. |
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| 作者姓名： | 王灿 时景璞 付凌雨 王海龙 周波 李辉 腾文禹 董亚珞 董卫 富成国 王文利 |
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| 作者单位： | 中国医科大学附属第一医院临床流行病教研室;中国医科大学附属第一医院流行病教研室;中国医科大学附属第一医院临床流行临床病教研室;中国医科大学附属第一医院神经内科;彰武县卫生局; |
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| 基金项目： | 国家自然科学基金(3067179630800944); 辽宁省科技厅基金(2005225010-2) |
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| 摘 要： | 目的探讨农村地区人群血清脂联素(adiponectin,APN)水平及其在脑卒中发病中的作用。方法采用整群随机抽样方法对辽宁省彰武县农村人群进行脑卒中患病情况调查,并从中随机抽取脑卒中患者和健康者各120例进行病例对照研究。结果脑卒中和健康者血清APN水平比较,脑卒中患者血清APN水平(7.414±5.595)mg/L低于对照组(9.471±5.601)mg/L,差异有统计学意义(P<0.05);脑卒中组和对照组血清APN水平与是否伴高血压有关,单纯脑卒中组、脑卒中合并高血压组与无脑卒中无高血压组相比APN水平下降,差异有统计学意义(P<0.05),单纯脑卒中组与单纯高血压组相比APN水平下降,差异有统计学意义(P<0.05),单纯脑卒中组与脑卒中合并高血压组相比APN水平下降,差异有统计学意义(P<0.05)。脑卒中危险因素的非条件Logistic回归分析显示,血清APN水平下降和收缩型高血压可能是脑卒中的独立危险因素(APN:OR=4.019,95%CI:2.092～7.722;收缩压:OR=3.864,95%CI:2.106～7.087)。血清APN水平影响因素多元逐步回归分析显示,体质指数(BMI)、...
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| 关 键 词： | 脂联素 脑卒中 危险因素 |
A case-control study on the relationship between serum adiponectin levels and stroke in rural areas of Zhangwu County in Liaoning Province |
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| WANG Can,SHI Jing-pu,FU Ling-yu,WANG Hai-long,ZHOU Bo,LI Hui,TENG Wen-yu,DONG Ya-luo,DONG Wei,FU Cheng-guo,WANG Wenli..A case-control study on the relationship between serum adiponectin levels and stroke in rural areas of Zhangwu County in Liaoning Province[J].Chinese Journal of Disease Control and Prevention,2011(1):11-14. |
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| Authors: | WANG Can SHI Jing-pu FU Ling-yu WANG Hai-long ZHOU Bo LI Hui TENG Wen-yu DONG Ya-luo DONG Wei FU Cheng-guo WANG Wenli |
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| Affiliation: | WANG Can1,SHI Jing-pu1,FU Ling-yu1,WANG Hai-long1,ZHOU Bo1,LI Hui1,TENG Wen-yu2,DONG Ya-luo1,DONG Wei1,FU Cheng-guo3,WANG Wenli3.1.Department of Clinical Epidemiology,the First Hospital of China Medical University,Shenyang 110001,China,2.Department of Neurology,3.Health Bureau of Zhangwu,Fuxin 123100 |
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| Abstract: | Objective To study the association of serum APN level with stroke in rural areas.Methods Using the method of clustering multistage sampling method,the population in rural areas,were investigated for the risk factors of stroke.Using simple random sampling method,Several cases of stroke patients and healthy persons were selected to carry out case-control study.Results The comparison of APN levels between stroke patients and healthy persons showed that APN level was lower in case group than in control group(7.... |
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| Keywords: | Adiponectin Stroke Risk factors |
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