图像引导放疗治疗颈段、胸上段食管癌疗效观察 |
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引用本文: | 胡智刚,张红雁,钱立庭,马军.图像引导放疗治疗颈段、胸上段食管癌疗效观察[J].现代保健,2014(19):135-137. |
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作者姓名: | 胡智刚 张红雁 钱立庭 马军 |
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作者单位: | 安徽医科大学附属省立医院肿瘤,安徽合肥230001 |
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摘 要: | 目的:观察颈段、胸上段食管癌行图像引导放射治疗(image-guided radiation therapy,IGRT)的疗效和不良反应。方法:回顾性分析32例颈段、胸上段食管癌患者接受图像引导放射治疗的疗效,局部区域控制率和总生存率用Kaplan-Meier法计算,并评价其毒副反应。结果:近期总有效率(CR+PR)为93.7%,1、2年局部控制率分别为84.3%、71.8%。1、2年生存率分别为75.0%、62.5%。急性放射反应主要是1、2度急性放射性食管炎,放射性气管炎,白细胞减少。结论:颈段胸上段食管癌行IGRT治疗疗效肯定,副反应小,临床值得推广。
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关 键 词: | 颈段胸上段食管癌 图像引导放射治疗 |
The Effect of Image-guided Radiation Therapy for Cervical and Upper-thoracic Esophageal Cancer |
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Affiliation: | Hu Zhi-gang,ZHANG Hong-yan,QIAN Li-ting,(The Affiliated Provincial Hospital of Anhui Medical University,efei 230001,China) |
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Abstract: | Objective: To observe the effects and side effects of (image-guided radiation therapy, IGRT) in the treatment of cervical and upper-thoracic esophageal carcinoma.Method: 32 cases with cervical and upper-thoracic esophageal carcinoma treated with IGRT were collected, their clinical data were analyzed retrospectively, acute toxi-cities and local control rates and overall survival rates were evaluated by Kaplan-Meier method.Result: The overall response rate (CR+PR) was 93.7%, the 1,2 year local control rate was 75%, 62.5% respectively, the 1,2 year overall survival rate was 75%, 62.5% respectively. Grade Ⅰ-Ⅱ acute esophagitis and bronchitis and decrease of white blood cells were the most common radiation side effects.Conclusion: IGRT can be considered as an effective and feasible approach to cervical and upper-thoracic esophageal carcinoma treatment, the side effects are slight. It’s worth promoting in clinical practice. |
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Keywords: | Cervical and upper-thoracic esophageal carcinoma Image-guided radiation therapy |
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