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肿瘤标志物的联合检测在胰腺癌诊断中的应用
引用本文:彭莉,李春岚,朱传金,王更记. 肿瘤标志物的联合检测在胰腺癌诊断中的应用[J]. 肿瘤基础与临床, 2006, 19(1): 30-31
作者姓名:彭莉  李春岚  朱传金  王更记
作者单位:山东省肿瘤防治研究院检验科,山东,济南,250117;山东省肿瘤防治研究院检验科,山东,济南,250117;山东省肿瘤防治研究院检验科,山东,济南,250117;山东省肿瘤防治研究院检验科,山东,济南,250117
摘    要:目的探讨肿瘤标志物联合检测在胰腺癌诊断中的应用价值。方法采用电化学发光法对胰腺癌患者的血清CA19_9、CA242和CEA进行检测。结果3种肿瘤标志物中敏感性和特异性以CA19_9最好,分别为82.0%和79.8%,联合检测三种肿瘤标志物可提高其敏感性,敏感性可达89.0%。结论联合检测肿瘤标志物有助于胰腺癌的早期诊断。

关 键 词:肿瘤标志物  胰腺癌  联合检测
文章编号:1003-1464(2006)01-0030-02
收稿时间:2005-06-28
修稿时间:2005-06-28

A Study the Value of Combined Measurement of Serum Tumor Markers in Diagnosis of Pancreatic Cancer Patients
Peng Li,Li Chunlan,Zhu Chuanjin,Wang Gengji. A Study the Value of Combined Measurement of Serum Tumor Markers in Diagnosis of Pancreatic Cancer Patients[J]. Journal of Basic and Clinical Oncology, 2006, 19(1): 30-31
Authors:Peng Li  Li Chunlan  Zhu Chuanjin  Wang Gengji
Affiliation:Laboratory Shandong Tumor Hospital, Jinan 250117, China
Abstract:Objective To study the value of combined measurement of multiple serum tumor markers in diagnosis of pancreatic cancer patients.Methods We detected tumor markers CA19_9,CA242 and CEA in patients with pancreatic cancer by electrochemi_luminescence immunoassay(ECLI).Results Among these tumor markers:CA19_9 was the best diagnostic index;its sensitivity and specificity were 83.2% and 75.8%,respectively.The sensitivity of combined assay was 89.0%.Conclusions These results suggest that the combined assay of tumor markers is helpful in the early diagnosis of pancreatic cancer.
Keywords:tumor markers  pancreatic cancer  combination assay
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