促红细胞生成素心肌保护作用的研究进展

促红细胞生成素（erythropoietin，EPO）是一种造血细胞生长因子，主要用于治疗多种原因所致的贫血。近年来其非造血生物作用逐渐引起关注，EPO具有组织保护作用，这一作用涉及多种不同组织和细胞，心肌保护一直是心血管病研究领域重要、关键的课题。EPO对心肌保护的作用近两年已渐有报道，这无疑为临床心肌保护的研究提供了新的思路和方向。现就EPO心肌保护作用的相关研究成果、发现以及有待解决的问题作一综述。

Advances in Erythropoietin's Myocardial Protective Effects

Erythropoietin(EPO) is known as a classical hematopoietic growth factor,which has been used to treat anemia caused by different reasons.In recent years,EPO's non-hematopoietic biological effects have gradually become a focus.Among these effects,EPO's tissue protection is most attractive and EPO has been proved to protect many different tissues and organs.Myocardial protection has always been the important and key topic in the field of cardiovascular diseases.Reports about EPO's myocardial protective effects have been published in the recent two years,which direct the research about myocardial protection with new ideas.In this article,the discoveries and unsolved problems associated with EPO's myocardial protection were reviewed.