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Efficient construction of 1,2-dihydroquinoline and 1,2,3,4-tetrahydroquinoline rings using tandem Michael-aldol reaction |
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| Authors: | Kazuishi MakinoOsamu Hara Yuko TakiguchiTakayuki Katano Yumiko AsakawaKeiichiro Hatano Yasumasa Hamada |
| Affiliation: | a Graduate School of Pharmaceutical Sciences, Chiba University, Yayoi-cho, Inage-ku, Chiba 263-8522, Japan b Faculty of Pharmacy, Meijo University, 150 Yagotoyama, Tempaku-ku, Nagoya 460-8503, Japan c Graduate School of Pharmaceutical Sciences, Nagoya City University, Tanabe-dori, Mizuho-ku, Nagoya 467-8603, Japan |
| Abstract: | 1,2-Dihydroquinolines and a 1,2,3,4-tetrahydroquinoline were efficiently constructed using tandem Michael-aldol reaction starting from N-protected o-aminobenzaldehydes and α,β-unsaturated carbonyl compounds in good yield. |
| Keywords: | 1 2-dihydroquinoline 1 2 3 4-tetrahydroquinoline tandem Michael-aldol reaction |
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