| 微通道电泳芯片系统中信号识别算法的设计与实现 |
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| 引用本文： | 李铁,金庆辉,陈继锋,赵建龙,徐元森.微通道电泳芯片系统中信号识别算法的设计与实现[J].功能材料与器件学报,2002,8(4):365-368,372. |
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| 作者姓名： | 李铁 金庆辉 陈继锋 赵建龙 徐元森 |
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| 作者单位： | 中国科学院上海微系统与信息技术研究所,上海,200050 |
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| 摘 要： | 介绍适用于微通道电泳芯片系统的DNA测序软件的总体流程，以及其中的信号处理与识别算法。以激光诱导荧光检测系统所采集到的原始数据为源信号，以小波平滑和小波去噪为理论基础，将滤波算法和峰值识别算法综合在一起进行设计，从而使其适用于检测速度更快、样品量更少的微通道电泳芯片系统。将本算法应用于DNA片段的分离实验中，可以有效地达到滤波以及信号识别的目的。
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| 关 键 词： | 微通道电泳芯片系统 DNA测序 小波分析 滤波算法 信号识别 |
| 文章编号： | 1007-4252(2002)04-0365-04 |
Design and implement of algorithm for signal identification in micro-channel electrophoresis system |
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| LI Tie,JIN Qing-hui,CHEN Ji-feng,ZHAO Jian-long,XU Yuan-sen.Design and implement of algorithm for signal identification in micro-channel electrophoresis system[J].Journal of Functional Materials and Devices,2002,8(4):365-368,372. |
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| Authors: | LI Tie JIN Qing-hui CHEN Ji-feng ZHAO Jian-long XU Yuan-sen |
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| Abstract: | A new method of signal identification used in micro-channel electro phoresis system was reported. Wavelet analysis which is the key algorithm for denoising was studie d. Combined with peakidentification and other components, a software for signal process and data an alysis was designed. Used in the separation experiment of DNA segments, the algorithm is proved to be av ailable and effective, and the results show that the signal to noise (S/N) can be greatly improved. |
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| Keywords: | micro-channel electrophoresis system wavelet analysis filter algori thm signal identification |
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