The in vitro antioxidant properties of the Al-quercetin/βCD and Al-catechin/βCD inclusion compounds, rationalized in terms of their electrochemical behaviour |
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Authors: | Karina Dias Sofia Nikolaou Wagner F. De Giovani |
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Affiliation: | 1. Departamento de Física e Química, Faculdade de Ciências Farmacêuticas de Ribeir?o Preto, Universidade de S?o Paulo, Av. do Café s/n, Ribeir?o Preto, SP, 14040-903, Brazil 2. Departamento de Química, Faculdade de Filosofia Ciências e Letras de Ribeir?oPreto, Universidade de S?o Paulo, Av. Bandeirantes 3900, Ribeir?o Preto, SP, 14040-901, Brazil
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Abstract: | Inclusion compounds of Al-quercetin and Al-catechin complexes with β-cyclodextrin (βCD) were investigated. The complex and the inclusion compound of quercetin are more effective DPPH? scavengers than the corresponding catechin compounds and the inclusion does not compromise their scavenging abilities, with only a slight decrease in the EC50 values. This is in accordance with the electrochemical data, which revealed that the inclusion compounds have lower diffusion coefficients in aqueous solution than the non-included compounds. For the quercetin compounds, some spectroscopic properties were also addressed by means of UV–visible and NMR measurements in aqueous media. |
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