药物涂层球囊治疗股总动脉病变的有效性及安全性

目的观察药物涂层球囊(DCB)治疗股总动脉病变的有效性和安全性。方法回顾性分析11例接受DCB治疗的股总动脉病变患者。结果 11例中,股总动脉闭塞7例,重度狭窄4例;9例为原发病变引发狭窄,2例为支架内再狭窄;股总动脉病变累及股浅动脉5例,单纯股总动脉病变6例。5例接受减容联合药物球囊、6例接受单纯药物球囊治疗,技术成功率100%。术后均未出现相关并发症,术后30天内无死亡。有效随访10例,随访12个月,累积一期通畅率为85.75%,均未行靶病变重建,2例发生截肢;术后12个月Rutherford分级及踝肱指数(ABI)均较术前明显改善(P均0.05)。结论 DCB治疗股总动脉病变短期疗效好,安全性高。

Efficacy and safety of drug-coated balloon for treatment of common femoral artery lesions

Objective To observe the clinical efficacy and safety of drug-coated balloon (DCB) for treating common femoral artery lesions. Methods Eleven patients of single common femoral artery lesions treated with DCB were retrospectively analyzed. Results Among 11 cases, there were 7 cases of common femoral artery occlusion and 4 cases of severe stenosis, including 9 cases of primary lesions and 2 cases of in-stent restenosis, common femoral artery alone in 6 cases, and common femoral artery disease involved superficial femoral artery in 5 cases. The technical success rate was 100%. No treatment-related complication was observed. No death occurred within 30 days after operation. Ten patients were followed up, and 12-month primary patency rate was 85.75%. No target lesion reconstruction was performed, while 2 patients underwent major amputation. Rutherford categories and ankle brachial index (ABI) values were significantly improved on 12-month follow-up compared with those before operation (both P<0.05). Conclusion DCB has good short-term efficacy and high safety for treatment of common femoral artery lesions.