| 奥扎格雷钠治疗急性脑梗死的临床观察 |
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| 引用本文： | 李家霞,韩春赓,傅佳. 奥扎格雷钠治疗急性脑梗死的临床观察[J]. 安徽医药, 2009, 13(4): 425-427 |
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| 作者姓名： | 李家霞 韩春赓 傅佳 |
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| 作者单位： | 安徽医科大学第一附属医院神经内科,安徽,合肥,230022;安徽医科大学第一附属医院神经内科,安徽,合肥,230022;安徽医科大学第一附属医院神经内科,安徽,合肥,230022 |
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| 摘 要： | 目的观察奥扎格雷钠治疗急性脑梗死的临床疗效和安全性。方法采用随机对照方法将178例急性脑梗死患者分为治疗组（奥扎格雷钠组）和对照组,两组分别在治疗前和治疗后7 d、14 d进行神经功能缺损评分、临床疗效评定并测定血浆纤维蛋白原（FIB）和D-二聚体等指标。结果与对照组比较,治疗组患者神经功能缺损评分的降低和临床疗效的改善差异均有显著性（P〈0.05）;治疗组治疗后7 d、14 d血浆FIB的浓度降低,治疗后7 dD-二聚体的浓度增加,14 dD-二聚体的浓度降低,差异具有显著性（P〈0.05）。结论奥扎格雷钠能够降低纤维蛋白原,改善急性脑梗死患者的神经功能缺损,临床疗效显著。
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| 关 键 词： | 奥扎格雷钠 急性脑梗死 治疗 |
Clinical effect of ozagrel sodium on acute cerebral infarction |
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| LI Jia-xia,HAN Chun-geng,FU Jia. Clinical effect of ozagrel sodium on acute cerebral infarction[J]. Anhui Medical and Pharmaceutical Journal, 2009, 13(4): 425-427 |
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| Authors: | LI Jia-xia HAN Chun-geng FU Jia |
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| Affiliation: | LI Jia-xia,HAN Chun-geng,FU Jia(Department of Neurology,The First Affiliated Hospital of Anhui Medical University,Hefei 230022) |
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| Abstract: | Aim To investigate the effect of ozagrel sodium on acute cerebral infarction and its influence on fibrinogen and plasma D-dimer content.Methods 178 patients with acute cerebral infarction were randomly divided into control group and treatment group.The patients in control group were treated with fleabane,while the patients in treatment group were treated with ozagrel sodium and fleabane.The neurologic impairment score and was evaluated the content of fibrinogen and plasma D-dimer pre-and post-therapy 7th,14... |
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| Keywords: | sodium ozagrel acute cerebral infarction therapy |
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