61例男性银屑病患者骨量结果分析

目的本研究旨在通过对男性银屑病患者代谢的影响因素的分析,探讨骨质疏松与银屑病的关系,为进一步预防及治疗提供依据。方法本组61例明确诊断的男性银屑病患者均来自我院皮肤科门诊,同时根据年龄、体重指数、族别选择61例同期在我院体检中心体检的男性志愿者进行配对研究。记录并分析了患者静脉血测定血清钙、磷、碱性磷酸酶,并进行骨密度测定。结果两组钙、磷及碱性磷酸酶水平无明显差异,银屑病组血清钙略低于对照组,但无统计学差异,而血清磷水平平均差异不显著;2组腰椎及股骨颈骨密度比较,银屑病组均低于对照组,且有统计学意义;进一步分析发现银屑病组股骨颈骨密度下降较明显,其差异具有统计学意义。股骨颈骨密度值比较,银屑病组无论是骨量减低还是骨质疏松患者比例明显高于非银屑病组。结论男性银屑病患者骨代谢水平明显下降。

Analysis of the bone mass in 61 male patients with psoriasis

Objective By analyzing the influential factors in male patients with psoriasis, to investigate the relationship between osteoporosis and psoriasis, and to provide theoretical basis for the prevention and treatment. Methods All the 61 male patients with psoriasis in this study were selected from the Out-patient Department of Dermatology in our hospital. Simultaneously, 61 male volunteers, who received health examination in our medical examination center, were selected as matched-pairs according to age, body mass index, and the nationality. The serum calcium, phosphorus, and alkaline phosphatase (ALP) of all the patients were recorded and analyzed. The bone mineral density of all the patients was also detected. Results The serum calcium, phosphorus, and ALP in two groups showed no significant difference. The serum level of calcium in psoriasis group was slightly lower than that in control group, but with no significant difference. And the serum level of phosphorus also showed no significant difference. BMD of the lumbar vertebrae and the femoral neck in psoriasis group was significantly lower than that in control group. Further analysis revealed that BMD of the femoral neck in psoriasis group decreased significantly. BMD of the femoral neck in psoriasis group, either in patients with bone mass loss or in patients with osteoporosis, was significantly higher than that in control group. Conclusion The bone metabolism level in male patients with psoriasis decreases significantly.