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慢性乙肝湿热中阻证辨证客观化相关因素多元统计学分析
引用本文:冯培民,陈蕾,谢朝良,孙同郊,龚枚. 慢性乙肝湿热中阻证辨证客观化相关因素多元统计学分析[J]. 中华中医药杂志, 2008, 23(12): 1060-1063
作者姓名:冯培民  陈蕾  谢朝良  孙同郊  龚枚
作者单位:[1]成都中医药大学附属医院消化内科,成都610075 [2]四川大学华西医院神经内科,成都610041 [3]广东省中山火炬职业技术学院生物医药系,中山528436 [4]泸州医学院附属第二医院肝胆内科,泸州646000
基金项目:四川省中医管理局应用研究科研基金课题
摘    要:目的:运用多元统计学方法分析慢性乙肝湿热中阻证与非湿热中阻证的多种指标,以期发现对慢性乙肝湿热中阻证辨证最有价值的指标并建立相关判别方程式.方法:按纳入标准选取2004-2005年泸州医学院第二医院肝病门诊慢性乙肝患者250例,分为湿热中阻证组和非湿热中阻证组,对其24项指标采用多元统计方法分析,建立湿热中阻证逐步判别方程和逐步logistic判别方程,并验证效能.结果:天门冬氨酸氨基转移酶(AST)、总胆红素(TBIL)、乙型肝炎e抗原(HBeAg)、舌质颜色、舌苔在两证间有显著性差异,是方程纳入指标;所建立两判别方程的准确度、敏感度和特异度分别为80.0%、71.4%、89.7%和84.8%、84.2%、85.5%.结论:上述5项指标在慢性乙肝湿热中阻证中医辨证中具有重要价值,所得方程式经交互验证后效能较高,具有较高的临床实用性.

关 键 词:慢性乙型病毒性肝炎  辨证客观化  湿热中阻证  多元统计学分析

Multi-statistical analysis of correlation factor of objective differentiation of symptoms and signs of stagnation of damp-heat in middle-jiao syndrome of chronic viral hepatitis B.
FENG Pei-min,CHEN Lei,XIE Chao-liang,SUN Tong-jiao,GONG Mei. Multi-statistical analysis of correlation factor of objective differentiation of symptoms and signs of stagnation of damp-heat in middle-jiao syndrome of chronic viral hepatitis B.[J]. China Journal of Traditional Chinese Medicine and Pharmacy, 2008, 23(12): 1060-1063
Authors:FENG Pei-min  CHEN Lei  XIE Chao-liang  SUN Tong-jiao  GONG Mei
Affiliation:FENG Pei-min1,CHEN Lei2,XIE Chao-liang3,SUN Tong-jiao3,GONG Mei1(1Department of Gastroenterology,Affiliated Hospital of Chengdu University of TCM,Chengdu 610075,China,2Department of Neurology,West China Hospital,Sichuan University,Chengdu 610041,3Department of biology-medicine,zhong shan Torch Vocational & Technical College,Zhongshan 528436,4Hepatobiliary Department,The Second Affiliated Hospital of Luzhou Medical College,Luzhou 646000,China)
Abstract:Ojective:To get significant indexes of stagnation of damp-heat in middle-jiao of chronic viral hepatitis B and to establish valuable and effcient multivariant discriminant function in relation to clinical TCM differentiation of symptoms and signs about it by multi-statistical method.Methods:Choose 250 chronic viral hepatitis B patients who meet the entry criterion,from the out-patient department of specialist of hepatopathy in the second hospital affiliated to Lu Zhou Medical College during 2004-2005,and di...
Keywords:Chronic viral hepatitis B  Objective differentiation of symptoms and signs  Stagnation of damp-heat in middle-jiao syndrome  Multi-statistical analysis  
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