A型肉毒毒素治疗面肌、眼睑痉挛156例临床观察

目的 探讨A型肉毒毒素治疗面肌，眼睑痉挛及Meige综合征的疗效。方法 采用A型肉毒毒素局部注射治疗偏侧面肌痉挛102例。眼睑痉挛41例及Meige综合征13例。并使用Cohen和Albert量表进行评估。结果 症状完全缓解占51.3%。明显改善占37.8%。部分改善占10.9%。疗效平均持续约3-6个月。复发者重复注射仍有效，出现眼睑闭合不全，面肌无力，眼睑下垂共58例，均恢复。结论 局部注射A型肉毒毒素确为一种安全有效。简便易行的治疗面肌。眼睑痉挛及Meige综合征的方法。

Clinical observation of therapeutic effects botulin a on 156 hemifacial spasm patients,blepharospasm patient and meige syndrome patients

Objective To investigate the therapeutic efficacy of botulin A on hemificial spasm patients, blepharospasm patients and meige syndrome patients. Methods A total of 158 patients, including 102 HFS patients, 41 BS patients and 13 meige syndrome patients, were studied on therapeutic efficacy of multifocal facial injctions with botulin A and were tested with cohen and albert. Results 51.3% of the patients were completely relieved of symptoms, 37.8% were obviously relieved , 10.9% were partially relieved. The average of etherapeutic efficacy lasted 3 to 6 monthes. It was effective to the recurrent patients with therapeutic of repeated injections,58 patients were discovered with palpebra dysraphism?facial weakness/asthenia or palpebra ptosis, who were recovered. Conclusion The botulin A local injections could serve as a kind of safe, useful and easy treatment the patients with to HFS?BS and Meige syndrome.