| MAR与IBT2种方法检测抗精子抗体的比较研究 |
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| 引用本文： | 马乐,赵丽红,李坚,吴建淮,任爱国.MAR与IBT2种方法检测抗精子抗体的比较研究[J].首都医学院学报,2004,25(4):528-530. |
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| 作者姓名： | 马乐 赵丽红 李坚 吴建淮 任爱国 |
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| 作者单位： | 首都医科大学附属北京妇产医院泌尿外科
(马乐，赵丽红，李坚，吴建淮)，首都医科大学附属北京妇产医院泌尿外科(任爱国) |
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| 基金项目： | 首都医学发展科研 (2 0 0 2 3 0 78)资助项目 |
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| 摘 要： | 通过比较国产MAR AsAb试剂盒与进口IBT AsAb试剂盒 ,验证国产MAR AsAb试剂盒的真实性和可靠性。以进口IBT AsAb试剂盒为对照 ,对 42 0例不育症患者精液标本进行检测 ,比较抗精子抗体检出情况。发现 :国产MAR AsAb试剂盒与进口IBT AsAb试剂盒 ,阳性率分别为 8.8%和 8.3 % ,经配对 χ2 检验无显著差异 (P >0 .0 5 )。国产MAR AsAb试剂盒灵敏度为 94.6% ,特异度为 1 0 0 %。同一份精液标本重复检测 1 0次 ,变异系数CV =2 .5 9%。提示 :国产MAR AsAb试剂盒灵敏度高、特异性好、重复性高 ,符合临床诊断的要求。
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| 关 键 词： | 混合抗球蛋白反应试验 免疫珠试验 抗精子抗体 免疫性不育 |
| 收稿时间： | 2003-11-19 |
| 修稿时间： | 2003年11月19 |
Comparison of MAR-AsAb and IBT-AsAb for Detecting AsAb |
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| Ma Le,Zhao Lihong,Li Jian,Wu Jianhuai,Ren Aiguo.Comparison of MAR-AsAb and IBT-AsAb for Detecting AsAb[J].Journal of Capital University of Medical Sciences,2004,25(4):528-530. |
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| Authors: | Ma Le Zhao Lihong Li Jian Wu Jianhuai Ren Aiguo |
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| Affiliation: | Ma Le,Zhao Lihong,Li Jian,Wu Jianhuai,Ren Aiguo Department of Urology,Beijing Obstetrics and Gynecology Hospital,Affiliate of Capital University of Medical Sciences |
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| Abstract: | The aim was to investigate the authenticity and reliability of homebred MAR-AsAb kit, MAR-AsAb kit and IBT-AsAb(USA) kit were compared. AsAb was detected in 420 patients, IBT-AsAb(USA) were used as control. The positive rate of MAR was 8.6%, and the IBT was 8.3%. There was no difference between MAR and IBT, P>0.05. The same sperm was tested 10 times, CV was 2.59%. It suggests that MAR has high sensitivity and specificity and is fit for the clinical diagnose. |
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| Keywords: | MAR IBT anti-sperm antibody immunological infertility |
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