| 3种苯并咪唑类药物对大熊猫西氏贝蛔虫的驱虫效果初步观察 |
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| 引用本文： | 李才武,李果,王一,胡正泉,成彦曦,王群,何鸣,周宇,曾文,周继秋,瞿祖凤,张志忠,杨光友,谢约.3种苯并咪唑类药物对大熊猫西氏贝蛔虫的驱虫效果初步观察[J].四川动物,2019(3):300-304. |
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| 作者姓名： | 李才武 李果 王一 胡正泉 成彦曦 王群 何鸣 周宇 曾文 周继秋 瞿祖凤 张志忠 杨光友 谢约 |
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| 作者单位： | 中国大熊猫保护研究中心;大熊猫国家公园珍稀动物保护生物学国家林业和草原局重点实验室;沈阳森林动物园管理有限公司;国家林业和草原局野生动植物保护司;四川农业大学 |
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| 基金项目： | 大熊猫国家公园珍稀动物保护生物学国家林业和草原局重点实验室开放课题(CCRCGP181913);大熊猫西氏贝蛔虫驱虫药物的筛选及临床药效项目[WPC-20(16-18)-07] |
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| 摘 要： | 西氏贝蛔虫Baylisascaris schroederi是圈养大熊猫Ailuropoda melanoleuca最常见、危害最严重的一种体内寄生虫,采用药物驱虫是目前控制圈养大熊猫蛔虫病的主要措施。为了筛选有效的驱虫药物,本研究观察了3种苯并咪唑类药物(阿苯达唑片剂、芬苯达唑膏剂和甲苯咪唑片剂)对大熊猫蛔虫的驱虫效果,统计了驱虫前后粪检蛔虫卵转阴率及排虫情况。结果表明,除芬苯达唑按5 mg·kg^-1体质量口服,每天1次,连续服用2 d,效果较差外,3种药物按10 mg·kg^-1体质量口服,每天1次,连续服用2 d,用药安全且有较好的驱虫效果。
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| 关 键 词： | 大熊猫 西氏贝蛔虫 阿苯达唑 芬苯达唑 甲苯咪唑 驱虫 |
Preliminary Observation on the Anthelmintic Effect of Three Benzimidazole Drugs on Baylisascaris schroederi |
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| LI Caiwu,LI Guo,WANG Yi,HU Zhengquan,CHENG Yanxi,WANG Qun,HE Ming,ZHOU Yu,ZENG Wen,ZHOU Jiqiu,QU Zufeng,ZHANG Zhizhong,YANG Guangyou,XIE Yue.Preliminary Observation on the Anthelmintic Effect of Three Benzimidazole Drugs on Baylisascaris schroederi[J].Sichuan Journal of Zoology,2019(3):300-304. |
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| Authors: | LI Caiwu LI Guo WANG Yi HU Zhengquan CHENG Yanxi WANG Qun HE Ming ZHOU Yu ZENG Wen ZHOU Jiqiu QU Zufeng ZHANG Zhizhong YANG Guangyou XIE Yue |
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| Affiliation: | (China Conservation and Research Center for Giant Panda,Dujiangyan,Sichuan Province 611830,China;Key Laboratory of National Forestry and Grassland Administration on Conservation Biology of Rare Animals in the Giant Panda National Park,Dujiangyan,Sichuan Province 611830,China;The Company of Shenyang Forest Z0o,Shenyang 110000,China;Wildlife Conservation Management Department,National Forestry and Grassland Administration,Beijing 100714,China;Sichuan Agricultural University,Chengdu 611130,China) |
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| Abstract: | Baylisascaris schroederi is one of the most common and harmful endoparasites in captive giant pandas.Drug repellent is the main measure to control this ascariasis in captive giant pandas.In order to screen effective anthelmintic drugs,the anthelmintic effects of 3 benzimidazoles(albendazole tablets,fenbendazole ointment and mebendazole tablets)on B.schroederi were studied using egg negative rate and excretion rate.The results showed that the effectiveness of fenbendazole taken orally at 5 mg·kg^-1 body mass once a day for 2 days was poor.However,the 3 drugs had good anthelmintic effect on B.schroederi when they were orally administered at 10 mg·kg^-1 body mass once a day for 2 days. |
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| Keywords: | Ailuropoda melanoleuca Baylisascaris schroederi albendazole fenbendazole mebendazole expelling parasite |
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