Terminal‐specific PEGylation of polypeptides in a dilute solution |
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| Authors: | Jun Jim Wu Henry T. Peng Pang N. Shek |
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| Affiliation: | Defence Research and Development Canada–Toronto, Individual Readiness Section, Toronto, M3M 3B9 ON, Canada |
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| Abstract: | PEGylations of polypeptides with a four‐arm PEG (polyethylene glycol) in a dilute DMSO solution resulted in a successful conjugation with terminal specificity, which supports an intriguing PEGylation mechanism via conformational and kinetic control. © 2010 Crown in the right of Canada. J Appl Polym Sci, 2010 |
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| Keywords: | peptides modification star polymers PEGylation |
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