| 大肠癌区域性淋巴结中S-100~+细胞的研究 |
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| 引用本文： | 孟刚. 大肠癌区域性淋巴结中S-100~+细胞的研究[J]. 皖南医学院学报, 1993, 12(2): 86-88 |
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| 作者姓名： | 孟刚 |
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| 作者单位： | 安徽医科大学病解教研室，安徽医科大学附院病理科 230032皖南医学院病解教研室 |
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| 摘 要： | 应用S-100蛋白抗体对34例大肠癌局部引流淋巴结和18例慢性炎的淋巴结进行免疫组化染色。结果表明,S-100~+细胞在淋巴结中的数量与副皮质区淋巴组织的增生及窦组织细胞的增生成正相关。大肠癌无癌转移组及炎症组淋巴结中S-100阳性细胞数目较有癌转移组淋巴结中的多(P<0.01)。在有癌转移组,S-100阳性细胞主要分布在癌灶周围,似乎形成一条“防卫带”。上述结果提示,S-100阳性细胞参与机体的抗肿瘤免疫,可能与机体抵御癌转移关系密切。
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| 关 键 词： | 大肠癌 淋巴结 淋巴结炎 树突状细胞 S-100阳性细胞 |
S-100~+CELLS IN THE LYMPH NODES IN THE REGION OF LARGE INTESTINE CANCER |
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| Gong Xiuy et al. S-100~+CELLS IN THE LYMPH NODES IN THE REGION OF LARGE INTESTINE CANCER[J]. Acta Academiae Medicinae Wannan, 1993, 12(2): 86-88 |
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| Authors: | Gong Xiuy et al |
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| Abstract: | The distribution of S-100 protein positive cells in regional lymph nodes was in vcstigatcd in patients with largc intestine canccr(n=34) and chronic lymphadcnitis (n=18). The results showed paracortical and histiocytic changes were related to the density of S-100~+ cells in lymph nodes. The statistical analysis showed float the value of S-100~+ cells in the non-metastasized group and the inflamed group was significantly higher than the metastasized group. S-100~+ cells were concentrated near the foci of carcinoma in the metastized group. These suggest that S-100~+ cells may play an important role in host resistance to tumor and may be more directlv involved in the host immune reaction against metastasis of cancer. |
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| Keywords: | colonic neoplasms lymph nodes lymphadenitis dendritic cells S-100 positive cell. |
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