TEM Imaging of Mass-selected Polymer Molecules |
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| Authors: | Nasibulin Albert G Kauppinen Esko I Thomson Bruce A Fernandez de la Mora J |
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| Affiliation: | (1) VTT Processes, Aerosol Technology Group, P.O. Box 1401, Fin-02044 VTT, Finland;(2) MDS Sciex, 71 Four Valley Dr., Concord, Ontario, Canada, L4K 4V8;(3) Mechanical Engineering, Yale University, P.O. Box 208286, New Haven, CT 06520-8286, USA |
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| Abstract: | Polyethylene glycol (PEG) molecules with masses below 1300 amu are electrosprayed (ES) from solution, mobility-selected at high resolution in a differential mobility analyzer (DMA), collected on a grid and imaged by transmission electron microscopy (ES–DMA–TEM). The DMA resolves individual n-mers, and selects only one out of the many present in the original sample. Ion identity is established from parallel mass spectra (ES-MS). The images reveal spherical particles 1.46nm in diameter, in good agreement with the known ion mass and bulk density. The DMA-selection technique opens new paths for the study of very small particles. |
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| Keywords: | electrospray DMA MS TEM polymer particle aerosol |
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