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New 3-hydroxyflavone derivatives for probing hydrophobic sites in microheterogeneous systems |
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| Authors: | Turan Ozturk Andrey S Klymchenko Sule Oncul Sule Taskiran F Betul Kaynak Alexander P Demchenko |
| Affiliation: | a Department of Chemistry, Science Faculty, Istanbul Technical University, Maslak, Istanbul, Turkey b Départment de Pharmacologie et Physicochimie, Photophysique des Interactions Biomolécularies, UMR7175, Institut Gilbert Laustriat, Université Louis Pasteur (Strasbourg I), BP 60024, 76401 Illkirch, France c TUBITAK Research Institute for Genetic Engineering & Biotechnology, Gebze-Kocaeli, Turkey d Department of Engineering Physics, Hacettepe University, Beytepe, Ankara, Turkey e Palladin Institute of Biochemistry, Kiev, Ukraine |
| Abstract: | Nine new 3-hydroxyflavone derivatives as fluorescent molecular sensors having two well-separated emission bands were synthesized. These sensors can occupy well-determined locations and orientations in macromolecular ensembles, such as micelles due to their finely-tuned designs. These polarity-sensitive dyes can incorporate into the anhydrous hydrophobic core of aqueous micelles. |
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