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220株肠球菌的分布及耐药性研究
引用本文:严立.220株肠球菌的分布及耐药性研究[J].国际检验医学杂志,2012,33(7):809-810.
作者姓名:严立
作者单位:重庆医科大学附属第一医院检验科,400016
摘    要:目的 调查重庆市某医院肠球菌属细菌的临床分布及对常见抗菌药物的耐药性.方法 采集临床各科送检的标本,进行肠球菌细菌的分离和培养,使用Vitek-Compact系统对肠球菌细菌进行鉴定,采用仪器法检测抗菌药物的MIC值,并根据CLSI的指导原则判定细菌的耐药性.结果 共分离到220株非重复肠球菌,最常见菌种为粪肠球菌95株(43.2%)、屎肠球菌84株(38.2%)和鹑鸡肠球菌32株(14.5%).药敏试验结果表明,屎肠球菌的总体耐药率高于粪肠球菌;肠球菌属对四环素、红霉素、庆大霉素的耐药率较高,对万古霉素、利奈唑胺保持高度敏感性.结论 肠球菌感染以屎肠球菌和粪肠球菌为主,可引起多部位感染,且对临床常用抗菌药物严重耐药.

关 键 词:肠球菌属  耐药性  重庆

Clinical distribution and drug resistance analysis of 220 strains of Enterococcus
Yan Li.Clinical distribution and drug resistance analysis of 220 strains of Enterococcus[J].International Journal of Laboratory Medicine,2012,33(7):809-810.
Authors:Yan Li
Affiliation:Yan Li(Department of Clinical Laboratory,the First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China)
Abstract:Objective To analyze distribution and drug resistance of isolated Enterococcus in certain hospital in Chongqing.Methods Minimal inhibitory concentration(MIC) method was performed to determine the antimicrobial susceptibility.Data was analyzed by WHONET 5.5 software.Results 220 strains of Enterococcus were isolated,of which E.faeealis,E.faecium and E.gallinarum accounted for 43.2%(95/220),38.2%(84/220) and 14.5%(32/220) respectively.Drug resistance of E.faecium was higher than that of E faecalis.Enterococceus was resistant to Tetracycline,Erythromycin and Gentamycin,but highly sensitive to Vancomycin and Linezolid.Conclusion Enterococcus infection in many system might be mainly caused by E.faecalis and E.faecium with multi-drug resistance.
Keywords:Enterococcus  drug resistance  Chongqing
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