从络论治特发性肺纤维化的理论基础及中药复方的作用机制

阐述从络论治特发性肺纤维化的理论基础。结合近年从络论治特发性肺纤维化的中药复方相关文献报道,认为从络论治特发性肺纤维化以益气养阴、活血通络、化痰通络、理肺通络为主要治法,以调节细胞因子网络、抑制细胞外基质合成和促进其降解、调控氧化应激及凝血-纤溶系统等为主要作用机制以达到抗纤维化作用。

Analysis on the theoretical basis and mechanism of Chinese compound for the treatment of idiopathic pulmonary fibrosis in network

This paper introduces the theoretical basis for treatment of idiopathic pulmonary fibrosis in network, combining with literature reports of compound Chinese medicine for idiopathic pulmonary fibrosis (IPF) in recent years, and summarizes the main therapeuti  Methods: of supplementing qi and nourishing yin, activating blood to dredge collaterals, eliminating phlegm to dredge collaterals, regulating lung to dredge collaterals, etc. Aims to regulate the cytokine network, and inhibit extracellular matrix synthesis and promote its degradation, regulation of oxidative stress and coagulation fibrinolys.