| 不同来源的TIL临床应用研究 |
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| 引用本文： | 蔡晓敏,李彪如.不同来源的TIL临床应用研究[J].免疫学杂志,1996,12(4):251-253. |
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| 作者姓名： | 蔡晓敏 李彪如 |
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| 作者单位： | [1]上海第二医科大学附属瑞金医院 [2]上海第二医科大学微生物学教研室 |
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| 摘 要： | 以５１例晚期肿瘤患者作为研究对象，对其不同来源的肿瘤浸润淋巴细胞（ＴＩＬ）进行治疗研究，发现肿瘤组织来源的ＴＩＬ其有效率及一年生存率明显高于胸腹水及转移淋巴结的ＴＡＬ；其中肿瘤组织的ＴＩＬ，胸腹水、转移淋巴结的ＴＡＬ有效率分别为８０．９％、４０．０％、４６．６％；三者治疗肿瘤患者的一年生存率分别为８１．０％、４６．７％、６０．０％；另外发现胸腹水ＴＡＬ对实质性肿块治疗疗效较低，为４０％，其中静脉滴
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| 关 键 词： | 肿瘤浸润 淋巴细胞 TIL 肿瘤相关 TAL 临床应用 |
Clinical study on TILs of different sources |
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| Cai Xiaomin,Lu Jing,Hua Zude,Li Biaoru,Tong Shanqing.Clinical study on TILs of different sources[J].Immunological Journal,1996,12(4):251-253. |
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| Authors: | Cai Xiaomin Lu Jing Hua Zude Li Biaoru Tong Shanqing |
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| Abstract: | We have analysed the anticancer efficacy and one year overal survial rate of 51 patients treated with different source TILs.The efficacy rate(80.9%)and one year overal survial rate(81%)of TIL from solid tumors were higher than that of TAL from ascites and lymph nodes.The efficacy rate of TAL from ascites treated with sold tumor was 40%(vein injection 14.2%,local injection 62.5%).TAL was effective for ascite regression(local injection 74%,vein injection 28.5 %).It showed that TIL killed solid tumor more efficiently than TAL and TAL had effect on ascite regression by local injection. |
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| Keywords: | Tumor infiltrating lymphocytes(TIL) Tumor associated lymphocytes(TAL) |
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