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Cys-C/Cr不同时Cys-C在糖尿病合并肾损伤中的应用
引用本文:赵津彩,王跃海.Cys-C/Cr不同时Cys-C在糖尿病合并肾损伤中的应用[J].标记免疫分析与临床,2012,19(5):276-277.
作者姓名:赵津彩  王跃海
作者单位:河北省邯郸市冀中能源峰峰集团总医院,河北邯郸,056200;河北省衡水市第二医院,河北衡水,053000
摘    要:目的 探讨血清胱抑素C(Cys-C)在糖尿病合并肾损伤诊断中的应用价值.方法 将研究对象分为糖尿病组(98例),其中胱抑素C/肌酐( Cys- C/Cr)正常者(87例)为一组,异常者(11例)为另一组,健康对照组(32例),共三组.三组均检测血清胱抑素C(Cys-C),同时检测血肌酐(Cr)、尿素氮(BUN)、白蛋白(AlB)、尿酸(UA)等项目.结果 各生化指标对糖尿病合并肾功能损伤的检出百分率总体为:Cys- C/Cr正常者:Cys-C> Cr> BUN> AlB,UA.Cys- C/Cr异常者:Cys-C>AlB>Cr,BUN> UA.结论 在Cys- C/Cr正常及异常时,Cys-C检测均可提高糖尿病合并肾功能损伤的检出率.

关 键 词:血清胱抑素C  胱抑素C/肌酐  糖尿病合并肾损伤

Value of Cys-C in the Diagnosis of Diabetes Incorporate Renal Damage
ZHAO Jin-cai , WANG Yue-hai.Value of Cys-C in the Diagnosis of Diabetes Incorporate Renal Damage[J].Labeled Immunoassays and Clinical Medicine,2012,19(5):276-277.
Authors:ZHAO Jin-cai  WANG Yue-hai
Affiliation:(General hospital of Jizhong Energy Existed of Fengfeng Group Co.,LTD.Handan 056200 China)
Abstract:Objective To investigate the value of serum cystatin C(Cys-C) in the diagnosis of diabetes incorporate renal damage.Methods 98 patients with diabetes were divided into serum cystatin C/creatinine(Cys-C/Cr) normal group 87 patients)and abnormal groups(11 patients).The levels of Cys-C,serum creatinine(Cr),urea nitrogen(BUN),albumin(AlB) and uric acid(UA) in 98 diabetes patients and 32 health controls were determined.Results The detection percentage of biochemical indexes for diabetes incorporate renal damage in Cys-C/Cr normal patients group were in the order of Cys-CCrBuNAlB/UA;and in Cys-C/Cr abnormal patients group were in the order of Cys-CAlBCrBuNUA.Conclusion The detection of Cys-C could improve the detection rate of diabetes incorporate renal damage.
Keywords:Serum cystatin C  Cystatin C/creatinine(Cys-C/Cr)  Diabetes incorporate renal damage
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