2例垂体萎缩患者性功能障碍治疗始末

目的:补充引起勃起功能障碍的病因之一:垂体萎缩,分析性腺功能不足导致激素水平低下与勃起功能障碍、性欲障碍的关系。方法:回顾2例因垂体萎缩导致勃起功能障碍患者的详细病史、体格检查、实验室检查、诊断分析和治疗经过。结果:病例一在给予雄激素补充治疗后,勃起功能和性欲反应良好;病例二给予抗焦虑药、PDE5抑制剂和雄激素补充治疗后,除了患者自觉晨勃硬度较前改善外,性欲和同房成功率均无改善。结论:雄激素对性欲的产生和性功能的维持十分重要,但又不是唯一的因素,还受心理因素的影响。

Literature review of two cases of pituitary gland atrophy leading to erectile dysfunction

Objectives:To probe into the relationship between hypogonadotropic hypogonadism and erectile dysfunction (ED) or libido disorder since the pituitary gland atrophy is one of pathogenesis in erectile dysfunction.Methods:The clinical histories,physical examinations,laboratory tests,diagnostic analysis and treatment experiences in the two pituitary gland atrophy cases which leading to ED were retrospectively summarized.Results:One case who accepted testosterone replacement therapy had a good therapeutic effect and sexual response in treating erectile function.However,the other case who accepted antianxiety drugs,type-5 phosphodiesterase inhibitors and testosterone replacement therapy had no improvement in libido and intercourse rate except hardness in early morning suddenly.Conclusion:Androgen is very important in maintaining libido and sexual response,which are also affected by psychological factors.