应用Micro CT颌骨骨小梁微细解剖学分析

目的 探讨高分辨率的MicroCT在骨形态三维结构的技术特长.方法 共10例下颌骨标本被分为髁状突组和下颌骨体部组,20个volumeofinterests被图像分析软件建立,每组各10个.计算每个像元大小的每个参数的平均值和标准差,并反复用ANOVA检验不同参数的值之间是否存在统计学意义（P ＜0.05）.结果 在所有重建像元大小中,下颌骨体部组的骨体积与骨体积分数与18μm像元组相比较有显著意义（P ＜0.05）.在髁状突组中,比36μm大的像元大小有意义（P ＜0.05）,但像元大小在36μm时并未发现显著差异（P ＞0.05）.骨小梁厚度及数量在下颌骨体部组和髁状突组都有显著意义（P ＜0.05）.结论 MicroCT是一种快速、准确、不损伤标本内部结构有效的评价方法.

Anatomy analysis of Jaw trabecular bone subtle structure using Micro CT

Objective The purpose of this study morphological parameters of the three dimensional microstructure for mandibular trabecular bone which were measured with Micro CT. Methods A total of 10 patients with mandibular condyle specimen were divided into two types of trabecular bones, condyle and mandibular body. Ten volume of interests were created in each group and the total of twenty were measured. The mean value and standard deviation of each parameter in each reconstruction pixel size were calculated. Repeated ANOVA test was used to determine whether significant differences in the values from each parameter existed among the regions（P 〈 0.05） and the following results were drawn. Results The bone volume andbone volume fraction values from the mandibular body group when compared to 18 ~L m pixel grnupwere significant at all reconstruction pixel size.In condyle group, all pixel sizes greater than 36 um were significant（P 〈 0.05）, but no differences were noted from pixel size at 36 u m（P 〉 0.05）. The trahecular thickness and trabecular number from both condyle and mandibular body group were significant at all reconstruction pixel sizes（P 〈 0.05）. Conclusion Several parameters of Micro CT have shown that it is effective aproach for evaluation without intrinsic structure damage.