眼前节相干光断层扫描仪与Orbscan Ⅱ及超声法眼前节生物测量对比研究

目的 比较眼前节相干光断层扫描仪(AS-OCT)与Orbscan Ⅱ以及超声法眼的节生物测量结果,为临床应用提供参考:方法对33例(66只眼)近视眼患者分别行AS-OCT,Orbscan Ⅱ以及A型超声测量仪(DGH550和DGH4000)进行眼前节生物测量,获取角膜中央厚度(CCT),前房深度(ACD),角膜直径,瞳孔直径以及前房角度数,进行对比分析.结果 AS-OCT,Orbscan Ⅱ以及超声法测量CCT分别为(532.32±35.26)μm.(538.45±38.31)μm,(555.82±37.63)μm,两两比较各组差异均有统计学意义(P<0.01).相关性分析显示三种方法中两两间均呈正相关,相关系数r=0.92、0.91、0.95;ACD分别为(3.19±0.21)mm,(3.08±0.24)mm,和(3.27±0.23)mm,两两间差异也均有统计学意义(P<0.01). OCT法测量瞳孔直径为(5.5±0.93)mm,Orbscan法测量结果为(4.5±0.75)mm,二者相差(-1.00±0.68)mm.差异有统计学意义(t=11.95,P=0.000),95%置信区间(0.84,1.17). OCT测量房角度数均大于Orbscan测量结果,在180度二者相差1.58度,差异无统计学意义(t=1.58,P=0.119),在0度相差2.89度,差异有统计学意义(t=2.89,P=0.005).结论 AS-OCT测量角膜中央厚度较Orbscan Ⅱ以及超声法测量结果薄,前房深度较Orbscan结果深,更接近于超声测量结果.房角角度测量结果与Orbscan结果近似,且能直观显示房角结构;眼前节OCT快速,非接触,在眼前节生物测量有广泛的应用前景.

Comparatire study of anterior segment parameters measurement by OCT, Orbscan, and A-scan ultrasound

Objective To compare the accuracy of anterior segment OCT with Orbscan and A ultra-sound in measuring anterior segment parameters.Methods Anterior segment parameters in 66 eyes of 33 my-opic patients were measured with OCT, Orbscan and A-scan ultrasound.The central corneal thickness (CCT), anterior chamber depth (ACD)were acquired by the three methods, corneal diameter( W to W ), anterior cham-ber width,pupil diameter,and anterior chamber angle were measured by OCT and Orbscan.Results The CCTs were (532.32±35.26)μm,(538.45±38.31 )μm,and (555.82±37.63)μm,measured by AS-OCT, Orbscan,and A-scan ultrasound.There were significant differences between each of them (P <0.01 ),and also positive correlations were found.The ACD were ( 3.19±0.21 )mm, ( 3.08±0.24 )mm, and( 3.27±0.23 )mm, re-spectively measured by OCT, Orbcan and ultrasound.There were significant differences between each of them. Pupil diameterwere(5.5±0.93)mm,and(4.5±0.75)mm measured by OCT and Orbscan, The difference was(-1.00±0.68)mm,asignificantdifferencewasfound(t=1195,P=0.000),95%CI(0.84,1.17). Thedifferenceofanteriorcham-beranglewere 1.58° inposition 180° (P=0.119)and 2.89° in position 0° (P<0.01)measure by OCT and Orbscan.Conclusion The CCT was thinner obtained by OCT than by Orbscan and A-scan ultrasound,ACD was deeper than by Orbscan and more close to A-scan ultrasound.The anterior chamber angle were similar in both instruments. AS-OCT provide noncontact,rapid,simple and accurate anterior segment parameters and furthermore a clear ante-rior segment image.It is a useful instrument in measuring anterior segment parameters.