|
|||||
|
|
DNA flow cytometry in human testicular cancer |
|
| Authors: | Sophie D Fosså Erik O Pettersen Erik Thorud Jan-Egil Melvik Sigurd Ous |
| Affiliation: | 1. Department of Medical Oncology and Radiotherapy, Norsk Hydro''s Institute for Cancer Research, The Norwegian Radium Hospital, Montebello, 0310 Oslo 3 Norway;2. Department of Tissue Culture, Norsk Hydro''s Institute for Cancer Research, The Norwegian Radium Hospital, Montebello, 0310 Oslo 3 Norway;3. Department of Surgical Oncology, Norsk Hydro''s Institute for Cancer Research, The Norwegian Radium Hospital, Montebello, 0310 Oslo 3 Norway |
| Abstract: | DNA flow cytometry revealed aneuploid tumour stemlines in 19 of 20 primary testicular cancers without significant difference of the ploidy values between seminomas and non-seminomas. In 7 of 8 analyzable histograms the S-phase activity was 22-51%. A metastatic mature teratoma had 6% cells in S-phase. These results support the clinical observation that testicular cancer is usually a rapidly growing human tumour. The high percentage of aneuploidy in testicular cancer may be of clinical value in the diagnosis of this malignancy. |
| Keywords: | |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ | |
