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一起新型冠状病毒肺炎聚集性疫情调查
引用本文:孙倩莱,李作超,谭夏林,蒋永林,陈伯中,李谋壹,肖琦,徐善松,方虹英,吴青春,杨浩,黄超洋,罗垲炜,何方玲,胡世雄,高立冬.一起新型冠状病毒肺炎聚集性疫情调查[J].实用预防医学,2020,27(4):389-392.
作者姓名:孙倩莱  李作超  谭夏林  蒋永林  陈伯中  李谋壹  肖琦  徐善松  方虹英  吴青春  杨浩  黄超洋  罗垲炜  何方玲  胡世雄  高立冬
作者单位:1. 湖南省疾病预防控制中心,湖南 长沙 410005; 2. 永州市疾病预防控制中心,湖南 永州 425000; 3. 冷水滩区疾病预防控制中心,湖南 永州 425000; 4. 零陵区疾病预防控制中心,湖南 永州 425006; 5. 祁阳县疾病预防控制中心,湖南 祁阳 426100; 6. 江永县疾病预防控制中心,湖南 江永 425404
基金项目:湖南省科技厅课题(2020SK3012,湖南省新型冠状病毒感染的肺炎疫情监测系统研究);湖南省自然科学基金(2019JJ80115);湖南省卫生厅重点课题(No.A2011-006);湖南省卫生健康委员会科研计划课题(B2019036);湖南省卫生健康委员会科研计划课题(B2019039);科技部十三五科技重大专项课题:病毒性传染病病原谱和病毒基因变异变迁规律研究(课题编号:2018ZX10713002)。
摘    要:目的 通过对Y市一起新型冠状病毒肺炎聚集性疫情的调查,初步分析该病潜伏期、传染期、传播能力。 方法 应用现场流行病学方法调查病例及其密切接触者,采用实时荧光RT-PCR技术对采集咽拭子标本进行新型冠状病毒核酸检测。 结果 本起疫情一共发现13名确诊病例和4名无症状感染者,发生四代病例传播,平均代际间隔时间5.08 d,平均潜伏期5.44 d(2~10 d),部分病例发病前2 d已具备传染性;密切接触者中存在一定比例隐性感染者。病例检测时存在需要多次采样检测方能确诊的现象。 结论 新型冠状病毒传播能力强,存在潜伏期传播,存在无症状感染,需加强对密切接触者的追踪、管理等防控措施。

关 键 词:新型冠状病毒肺炎  聚集性疫情  传播链  潜伏期  无症状感染者  
收稿时间:2020-02-18

Clustering of coronavirus disease 2019:a brief report
SUN Qian-lai,LI Zuo-chao,TAN Xia-lin,JIANG Yong-lin,CHEN Bo-zhong,LI Mou-yi,XIAO Qi,XU Shan-song,FANG Hong-ying,WU Qing-chun,YANG Hao,HUANG Chao-yang,LUO Kai-wei,HE Fang-ling,HU Shi-xiong,GAO Li-dong.Clustering of coronavirus disease 2019:a brief report[J].Practical Preventive Medicine,2020,27(4):389-392.
Authors:SUN Qian-lai  LI Zuo-chao  TAN Xia-lin  JIANG Yong-lin  CHEN Bo-zhong  LI Mou-yi  XIAO Qi  XU Shan-song  FANG Hong-ying  WU Qing-chun  YANG Hao  HUANG Chao-yang  LUO Kai-wei  HE Fang-ling  HU Shi-xiong  GAO Li-dong
Affiliation:(Hunan Provincial Center for Disease Control and Prevention,Changsha,Hunan 410005,China;Yongzhou Municipal Center for Disease Control and Pret ention,Yongzhou,Hunan 425000,China;Lengshuitan District Center for Disease Control and Prevention,Yongzhou,Hunan 425000,China;Lingling District Center for Disease Control and Prevention Yongzhou,Hunan 425006,China;Qiyang County Center for Disease Control and Prevention,Qiyang,Hunan 426100,China;Jiangyong County Center for Disease Control and Prevention,Jiangyong,Hunan 425404,China)
Abstract:Objective To preliminarily analyze the latent period,infectious period and transmissibility of coronavirus disease 2019(COVID-19)through an investigation of a clustering epidemic of COVID-19 in Y city.Methods Field epidemiological method was used to survey the cases and related close contacts.Real time RT-PCR technique was used to detect 2019-nCoV nucleic acid in throat swab samples collected from the respondents.Results A total of 13 confirmed cases and 4 asymptomatic infections were discovered in the clustering epidemic,with the transmission passing through four generations.The average serial interval was 5.08 days,and the average incubation period 5.44 days(ranging between 2 and 10 days).Some confirmed cases were found to be contagious 2 days prior to the onset.There were some asymptomatic infections among the close contacts.Some cases were confirmed after several times of sample testing.Conclusions 2019-nCoV has a high transmissibility.There exist transmission during the incubation period and asymptomatic infection.It is necessary to intensify the prevention and control measures like follow-up and management of close contacts.
Keywords:COVID-19  clustering epidemic  transmission chain  latent period  patient with asymptomatic infection
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