| 了哥王抗炎有效部位研究 |
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| 引用本文： | 徐骏军,王国伟,熊友香,尤志勉. 了哥王抗炎有效部位研究[J]. 江西中医学院学报, 2014, 26(6): 40-41 |
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| 作者姓名： | 徐骏军 王国伟 熊友香 尤志勉 |
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| 作者单位： | 浙江中医药大学药学院 浙江杭州310053 |
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| 基金项目： | 浙江省教育厅科技计划项目 |
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| 摘 要： | 目的：研究了哥王的抗炎有效部位.方法：通过蛋清法致小鼠足肿胀实验及炎症部位PGE3含量测定,确定了哥王有效的抗炎部位.结果：阳性组、高剂量组和中剂量组小鼠足肿胀度明显降低（P＜0.05）,肿胀抑制率分别为44.75％、38.49％、29.26％.阳性组、高剂量组和中剂量组炎症部位的PGE2含量明显降低（P＜0.05）.结论：乙酸乙酯部位是了哥王的抗炎有效部位.
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| 关 键 词： | 了哥王 抗炎 有效部位 |
Study on Anti-inflammatory Effective Fraction of Wikstroemia Indica |
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| XU Jun-jun,WANG Guo-wei,XIONG You-xiang,YOU Zhi-mian. Study on Anti-inflammatory Effective Fraction of Wikstroemia Indica[J]. Journal of Jiangxi College of Traditional Chinese Medicine, 2014, 26(6): 40-41 |
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| Authors: | XU Jun-jun WANG Guo-wei XIONG You-xiang YOU Zhi-mian |
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| Affiliation: | XU Jun - jun, WANG Guo - wei, XIONG You - xiang, YOU Zhi - mian (Zhejiang Chinese Medical University, College of Pharmaceutical Science, Hangzhou 310053, China.) |
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| Abstract: | Objective： To study the anti -inflammatory effective fraction of Wikstroemia indica. Method： The mouse feet were injected by egg white, determinated content of arthritic PGE2 and determined the anti - inflammatory effective fraction of Wikstroemia indica. Results ： The positive group, high dose group and middle dose group around the feet weight was difference with the blank control group with significant difference （ P 〈 0.05 ） , the inhibition rate was 44.75% , 38.49% and 29.26% respectively. By measuring the content of PGE2, arthritic get positive group, high dose group and middle dose group OD value and the blank control group with significant difference （P 〈 0. 05 ）. Conclusion ： Ethyl acetate extraction of Wikstroemia indica is the anti - inflammatory effective fraction. |
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| Keywords: | Wikstroemia Indica Anti - inflammatory Effective Fraction |
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