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| 自身免疫性肝炎患者外周血中髓系来源抑制性细胞频率变化 | |
| 引用本文： | 李海文,徐向升,张政,林沪,曾珍,李元元,彭琼,李颖,王福生,戴夫. 自身免疫性肝炎患者外周血中髓系来源抑制性细胞频率变化[J]. 传染病信息, 2011, 24(1): 29-31 |
| 作者姓名： | 李海文 徐向升 张政 林沪 曾珍 李元元 彭琼 李颖 王福生 戴夫 |
| 作者单位： | 1. 安徽医科大学第三附属医院消化内科,合肥,230000 2. 解放军第三○二医院肝病生物治疗研究中心,北京,100039 3. 解放军第三○二医院肝脏肿瘤诊疗研究中心,北京,100039 |
| 基金项目： | 国家"十一五"科技重大专项 |
| 摘 要： | 目的 探讨自身免疫性肝炎(autoimmune hepatitis,AIH)患者外周血中髓系来源抑制性细胞(myeloid-derived suppressor cells,MDSCs)频率及其与疾病的关系.方法 采集22例AIH患者和24例健康对照者外周血,用流式细胞仪分析MDSCs频率,对患者MDSCs频率与肝脏生... |
| 关 键 词： | 肝炎,自身免疫性 肝硬化 T-淋巴细胞,调控 髓 免疫抑制 |
Frequency of myeloid-derived suppressor cells in peripheral blood in patients with autoimmune hepatitis |
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| LI Hai-wen,XU Xiang-sheng,ZHANG Zheng,LIN Hu,ZENG Zhen,LI Yuan-yuan,PENG Qiong,LI Ying,WANG Fu-sheng,DAI Fu. Frequency of myeloid-derived suppressor cells in peripheral blood in patients with autoimmune hepatitis[J]. Infectious Disease Information, 2011, 24(1): 29-31 | |
| Authors: | LI Hai-wen XU Xiang-sheng ZHANG Zheng LIN Hu ZENG Zhen LI Yuan-yuan PENG Qiong LI Ying WANG Fu-sheng DAI Fu |
| Affiliation: | LI Hai-wen,XU Xiang-sheng,ZHANG Zheng,LIN Hu,ZENG Zhen,LI Yuan-yuan,PENG Qiong,LI Ying,WANG Fu-sheng,DAI Fu Department of Gastroenterology,The Third Affiliated Hospital of Anhui Medical University,Hefei,Anhui 230000,China |
| Abstract: | Objective To investigate the frequency of myeloid-derived suppressor cells(MDSCs) in peripheral blood in patients with autoimmune hepatitis(AIH) and its correlation with disease progression.Methods Peripheral blood samples from 22 AIH patients and 24 healthy controls were collected.The frequency of MDSCs was analyzed using flow cytometry and its correlation with liver biochemical indicators was evaluated as well.Results The frequencies of MDSCs in non-cirrhotic AIH patients were higher than those in cirrhot... |
| Keywords: | hepatitis autoimmune liver cirrhosis T-lymphocytes regulatory marrow immunosuppression |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |
