小儿恶性骶尾部畸胎瘤的治疗及预后(附26例报告)

目的：探讨小儿恶性骶尾部畸胎瘤特点、诊治方法及预后。临床资料：26例中，男11例，女15例。病理分恶性畸胎瘤9例，卵黄囊瘤门例。结果：26例中，24例经手术治疗，其中16例为晚期肿瘤，术后自动出院，短期内死亡；6例分别于半年内死亡；1例原为良性，半后复发，再术后2个月死亡；1例卵黄囊瘤，术后坚持每月化疗1次，开始好，AFP下降，全身情况好，1年后复发，放弃治疗。结论：提出早诊断、早手术、术前明确诊断要点、术后采取联合化疗、放疗等综合措施。影响预后的主要因素是就诊太晚，特别是隐性患儿，肛诊易发现。

The Treatment and Prognosis of Malignant Sacrococcygeal Teratoma in Children (A Report of 26 Cases)

Object:To study the chaseteristic of malignant sacrococcygeal teratomas(SCTs) in chirdren and evaluate the diagnostic and therapeutic approach to there tumors and the effect on the Patients. Clinic data:26 PatientS presented SCTs, 11 of them were male and 15 female. Pathologically, 9 of them malignant teratomas and 17 yolk sac tumors. Result: Of the 26 SCTs,24 were treated surgically, them 16 had advanced tumor were dischaged from the hospital voluntarily, and died in a short for;6 died within 6 months respectively. One case of benign tomor originally recurred ther half a year and died 2 months later after reoperation One child with a yolk sac tumor was in a good condition at the begining and received chemotherapy once a month postoperatively, but one year later abstained ho management because of tumor recurrence. Conclusion: It was important to have early diagnosis, early operation, more accurate diagnosis before operation and comprebensive approach including combined chemotherapy, radation treatment ther operation. The main faCtor that affeCts Prognosis is to see doctors too late, especially for thOSe with latent tumors, but they can be easily determined by using digital examination.