| 含锌生物活性微晶玻璃的制备及研究 |
| |
| 引用本文： | 郭丽萍,李立华,雷家珩,牟善彬.含锌生物活性微晶玻璃的制备及研究[J].武汉理工大学学报,1993(1). |
| |
| 作者姓名： | 郭丽萍 李立华 雷家珩 牟善彬 |
| |
| 作者单位： | 武汉工业大学材料工程系
(郭丽萍，李立华，雷家珩)，武汉工业大学材料研究与测试中心(牟善彬) |
| |
| 摘 要： | 本工作通过引入ZnO制得了一种对人体代谢机能有促进作用的ZnO-MgO-CaO-B_2O_3-SiO_2-P_2O_5系统新型的生物活性微晶玻璃人工骨材料,并对玻璃的组成范围与熔制条件,晶化特性与热处理工艺制度、晶相以及ZnO含量对材料性能的影响、材料的生物相容性和生物活性等方面进行了较系统的研究。结果表明:该材料以氧磷灰石和β-硅灰石为主晶相;具有较高的力学强度(抗折强度170Mpa、抗压强度500Mpa)和良好的化学稳定性,在模拟生理体液中,可有控制地释出促进人体伤口愈合的Zn~(2+)离子。动物实验证明该材料具有良好的生物相容性和生物活性,有着良好的应用前景。
|
| 关 键 词： | 生物活性 微晶玻璃 人工骨材料 微量元素 伤口愈合 |
Preparation and Studies of Bioactive Glass-Ceramic Containing-Zn |
| |
| Guo Liping,Li Lihua,Lei Jiaheng Dept. of Materials Engineering,Wuhan University of Technology Mu Shanbin Material Research and Analysis Center,Wuhan University of Technology.Preparation and Studies of Bioactive Glass-Ceramic Containing-Zn[J].Journal of Wuhan University of Technology,1993(1). |
| |
| Authors: | Guo Liping Li Lihua Lei Jiaheng Dept of Materials Engineering Wuhan University of Technology Mu Shanbin Material Research and Analysis Center Wuhan University of Technology |
| |
| Abstract: | In present work, a new kind of bioactive glass-ceramics for artifical bones is pre-pared in the ZnO-MgO-CaO-B_2O_3-SiO_2-P_2O_5 system, which can help wounds heal and increase theimmunity of human bodies by introducing ZnO. The compositions of glasses and melting condition,crystallizing characteristics and heat treatment technique, effect of Zn content on properties of materi-al and biocompatibility and bioactivity of material were investigated systemtically. The experimentalresults indicated that material, with oxyapatite and wollastonite as main crystal phases, has high me-chanical strength (bending strength 170 MPa, compresive strength 500 MPa) and fine chemical sta-bility. Zn~(2+) ions released slowly out of glass-ceramic Sample in simulated physiological solution,whichwas beneficial to healing of wound. The animal experiment proved that material has good biocompati-bility and bioactive. |
| |
| Keywords: | bioactive glass-ceramic artificial bone materials trace element wound healing |
| 本文献已被 CNKI 等数据库收录！ |
|
