| 血浆C-反应蛋白与行支架植入术后的稳定性心绞痛患者预后的关系 |
| |
| 引用本文： | 徐延路,郑欣馨,朱成刚,郭远林,郑昕,滕思勇,高展,慕朝伟,袁晋青,李建军. 血浆C-反应蛋白与行支架植入术后的稳定性心绞痛患者预后的关系[J]. 中国分子心脏病学杂志, 2011, 11(2): 69-74 |
| |
| 作者姓名： | 徐延路 郑欣馨 朱成刚 郭远林 郑昕 滕思勇 高展 慕朝伟 袁晋青 李建军 |
| |
| 作者单位： | 北京协和医学院中国医学科学院阜外心血管病医院心内科,北京市西城区北礼土路167号,100037 |
| |
| 基金项目： | 阜外心血管病医院博士生培养基金，国家自然科学基金，北京市自然科学基金，教育部博士点基金 |
| |
| 摘 要： | 目的 C-反应蛋白(CRP)预测支架植入术后非靶血管病变的进展和靶病变的再狭窄。方法测定311例慢性稳定性心绞痛患者入院时及随访时的血浆CRP浓度。所有患者经皮冠状动脉支架植入术,并于6-9个月后行冠状动脉造影随访。结果进展组患者高敏CRP浓度高于非进展组患者[1.60(0.80-3.46)mg/lvs0.96(0.55-1.87)mg/l,P<0.001]。再狭窄组患者高敏CRP浓度高于非再狭窄组患者[1.46(0.90-2.90)mg/lvs1.15(0.59-2.34)mg/l,P=0.026]。多因素回归分析显示入院时血浆CRP是非靶血管病变狭窄快速进展的独立预测因子(OR=1.207,95%CI1.073-1.357,P=0.002)。结论血浆CRP可独立预测稳定性心绞痛患者支架植入术后非靶血管病变狭窄的快速进展,但与靶病变再狭窄无关。
|
| 关 键 词： | C-反应蛋白 炎症 稳定性心绞痛 经皮冠状动脉介入治疗 |
Relationship of Plasma C-reactive Protein with Prognosis of Patients with Stable Angina Pectoris after Coronary Stent Implantation |
| |
| XU Yan-Lu,ZHENG Xin-Xin,ZHU Cheng-Gang,GUO Yuan-Lin,ZHENG Xin,TEN Si-Yong,GAO Zhan,MU Chao-Wei,YUANJin-Qing,LI Jian-Jun. Relationship of Plasma C-reactive Protein with Prognosis of Patients with Stable Angina Pectoris after Coronary Stent Implantation[J]. Molecular Cardiology of China, 2011, 11(2): 69-74 |
| |
| Authors: | XU Yan-Lu ZHENG Xin-Xin ZHU Cheng-Gang GUO Yuan-Lin ZHENG Xin TEN Si-Yong GAO Zhan MU Chao-Wei YUANJin-Qing LI Jian-Jun |
| |
| Affiliation: | Department of Cardiology, Fu Wai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, BeiLiShi Road 167, Beijing 100037, China |
| |
| Abstract: | Objective We tested the hypothesis that elevation of inflammatory markers including C-reactive protein (CRP) on admission, irrelevant to PCI procedure, might indicate a progressive coronary de novo non-target lesion (NTL) as well as restenosis of stented target lesion (TL) in patients with stable angina (SA) after coronary stenting. Methods: We studied 311 consecutive SA Chinese patients who underwent diagnostic coronary angiography (CAG) and successful PCI with stent implantation on initial admission and C... |
| |
| Keywords: | C-reactive protein inflammation stable angina percutaneous coronary intervention |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
