2018—2020年苏州市5岁以下儿童感染性腹泻病原学及流行特征分析

目的 了解苏州市儿童感染性腹泻病原学和流行特征,为精准防控提供依据.方法 对2018—2020年在苏州市某国家级哨点监测医院开展感染性腹泻病原主动监测,对病例完成流行病学调查并采集粪便标本,对所有标本进行5种病毒和6类细菌检测和分型(群).结果 共纳入感染性腹泻病例999例,病原检出率为36.34％,病毒检出率为31....

Etiology and epidemic characteristics of infectious diarrhea in children under 5 years old in Suzhou in 2018-2020

Objective To investigate the etiology and epidemic characteristics of infectious diarrhea in children in Suzhou,and to provide a basis for accurate prevention and control.Methods Active surveillance of infectious diarrhea pathogens was carried out in a national sentinel surveillance hospital in Suzhou from 2018 to 2020.Epidemiological investigation was completed and stool samples were collected.All samples were detected and classified for 5 viruses and 6 types of bacteria.Results A total of 999 cases of infectious diarrhea were included,the detection rate of pathogen was 36.34%,virus was 31.41%,bacteria was 6.31%,and multi-pathogen mixed infection was 4.8%.The top three pathogens were rotavirus(17.92%),norovirus(12.51%)and Salmonella(3.4%).Both rotavirus diarrhea and norovirus diarrhea occurred most frequently in children aged 7-24 months,with peak incidence in winter and early spring.There was no obvious seasonal and age distribution of bacterial diarrhea.The multi-pathogen mixed infection was mainly virus-virus.G9P]8 was the dominant genotype of rotavirus,while type 2 was the dominant type of norovirus in the cases of infectious diarrhea.Conclusion Infectious diarrhea in children under 5 years old in Suzhou area from 2018 to 2020 is mainly caused by viruses,among which rotavirus and norovirus are the dominant pathogens.Viral diarrhea has obvious population distribution and seasonal characteristics.The dominant pathogens of bacterial diarrhea are Salmonella and diarrheagenic Escherichia coli.