33例导管内癌组织形态观察及发病年龄分析

目的观察导管内癌(intraductal carcinoma)组织形态及发病年龄分析,探讨两者关系。方法收集33例确诊导管内癌标本,通过HE染色及免疫组化染色,观察不同形态导管内癌形态特征,并进行发病年龄统计。结果 33例导管内癌中,乳头型2例(6.1%),低乳头型4例(12.1%),筛状型4例(12.1%),粉刺型8例(24.2%),实性型15例(45.5%)。结论导管内癌可有不同的形态特征。SMA、P63联合应用,对观察导管内癌是否出现微浸润有重要意义。导管内癌在各年龄组中的发生率并无差异。

Histomorphology and Analysis of Age in 33 Cases of Intraductal Carcinoma

ABSTRACT Objective: Observe the histomorphology of intraductal carcinoma and explore the relationship between the histomorphology and age of onset. Methods: 33 cases of intraductal carcinoma were collected to evaluate the morphological characteristics by HE staining and immune-histochemical staining, and the age of onset was analyzed. Results: During 33 cases of intraductal carcinoma, there were 2 cases of papillary(6.1%), 4 cases of low papillary(12.1%), 4 cases of cribriform(12.1%), 8 cases of comedo(24.2%), 15 cases of solid(45.5%). Conclusions: There were different morphological characteristics for intraductal carcinoma. It was important to detect the occurrence of micro-invasion for intraductal carcinoma by the use of SMA and P63 in combination. There were no differences for the incidence of intraductal carcinoma of the different age groups.