| 原发性肝癌TACE前后凝血指标的变化及临床意义 |
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| 引用本文： | 王彦春,刘树业,段樱,顾春刚. 原发性肝癌TACE前后凝血指标的变化及临床意义[J]. 上海医学检验杂志, 2010, 0(2) |
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| 作者姓名： | 王彦春 刘树业 段樱 顾春刚 |
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| 作者单位： | 天津医科大学;天津市第三中心医院; |
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| 摘 要： | 目的研究原发性肝癌介入治疗前后凝血指标的变化。方法采用全自动血凝分析仪检测65例肝癌患者介入治疗前后第1、3、5、15、30天的凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、凝血酶时间(TT)、纤维蛋白原(FIB)含量变化。结果介入治疗后第1天,PT、APTT较介入治疗前升高,差异有统计学意义(P<0.05);介入治疗5 d以后,PT较治疗前均表现为降低,差异有统计学意义(P<0.05);APTT介入治疗后15 d较治疗前降低,差异有统计学意义(P<0.05);术后第3、5天FIB含量较治疗前升高,差异有统计学意义(P<0.05),以后成渐进性下降趋势,术后30 d FIB较治疗前降低,差异有统计学意义(P<0.05);对于Child分级各组PT结果显示只有Child A级第5天以后,PT较治疗前表现为降低,差异有统计学意义(P<0.05)。结论肝癌介入治疗前后应加强观察,尤其在介入治疗早期,及时进行相应的实验室检查,以期早期发现,及时处理,防止弥散性血管内凝血(DIC)的发生,尤其对于Child C级的患者更应该注意。
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| 关 键 词： | 原发性肝癌 肝动脉化疗栓塞术 凝血指标 |
Changes of blood coagulation indicators in patients with primary liver cancer before and after TACE and its clinical significance |
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| WANG Yanchun,LIU Shuye,DUAN Ying,GU Chungang.. Changes of blood coagulation indicators in patients with primary liver cancer before and after TACE and its clinical significance[J]. Shanghai Journal of Medical Laboratory Sciences, 2010, 0(2) |
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| Authors: | WANG Yanchun LIU Shuye DUAN Ying GU Chungang. |
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| Affiliation: | WANG Yanchun1,LIU Shuye2,DUAN Ying2,GU Chungang2.(1.Tianjin Medical University,Tianjin 300070,China,2.Tianjin Third Central Hospital,Tianjin 300170,China) |
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| Abstract: | Objective To study the changes of blood coagulation indicators in patients with primary liver cancer before and after transcatheter arterial chemoembolization(TACE).Methods The changes of prothrombin time(PT),activated partial thromboplastin time(APTT),thrombin time(TT),and fibrinogen(FIB) content were determined by automated coagulation analyzer in 65 patients with liver cancer before treatment and in the 1,3,5,15 and 30 days after intervention treatment.Results In the first day of the intervention,the lev... |
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| Keywords: | Primary liver cancer Transcatheter arterial chemoembolization Coagulation indicator |
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