Nano‐Hydroxyapatite Improves the Properties of β‐tricalcium Phosphate Bone Scaffolds |
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| Authors: | Cijun Shuai Pei Feng Yi Nie Huanglong Hu Jinglin Liu Shuping Peng |
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| Affiliation: | 1. State Key Laboratory of High Performance Complex Manufacturing, Central South University, , Changsha, 410083 People's Republic of China;2. State Key Laboratory of Powder Metallurgy, Central South University, , Changsha, 410083 People's Republic of China;3. Department of Regenerative Medicine & Cell Biology, Medical University of South Carolina, , Charleston, South Carolina, 29425;4. Cancer Research Institute, Central South University, , Changsha, 410078 People's Republic of China |
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| Abstract: | β‐Tricalcium phosphates have been widely used as biomaterials for bone substitutes; however, the poor mechanical properties limit the application in bearing loading bones. In this study, nano‐hydroxyapatite has been introduced to improve the mechanical properties for porous bioceramic scaffolds. Nanocomposites containing 0–10 wt% needle‐like nano‐hydroxyapatite were prepared for investigation. It has been found that needle‐like nano‐hydroxyapatite improves the toughness, hardness, and compressive strength of the porous β‐tricalcium phosphates scaffolds, as well as the microstructure properties. The study provides a reference for the development of safe, excellent bone scaffolds for bone tissue engineering. |
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