| 胃癌组织中RhoC和TERT的表达及其临床意义 |
| |
| 引用本文： | 曲义坤,刘伟新,徐剑,吕淑慧. 胃癌组织中RhoC和TERT的表达及其临床意义[J]. 热带医学杂志, 2013, 13(5): 634-636,640 |
| |
| 作者姓名： | 曲义坤 刘伟新 徐剑 吕淑慧 |
| |
| 作者单位： | 佳木斯大学附属第一医院普外科,黑龙江佳木斯,154002 |
| |
| 基金项目： | 黑龙江省卫生厅科研资助项目 |
| |
| 摘 要： | 目的探讨RhoC和TERT蛋白在胃癌组织中的表达以及在胃癌发生发展过程中的作用。方法采用免疫组织化学方法检测105例胃癌组织中RhoC和TERT蛋白的表达。结果RhoC和TERT蛋白在胃癌组织中的表达与肿瘤浸润深度、组织类型、临床分期及淋巴结转移有明显相关性；RhoC和TERT蛋白在胃癌组织中的表达呈正相关。结论RhoC和TERT蛋白在胃癌的发生发展过程中可能具有一定的协同作用。
|
| 关 键 词： | 胃癌 RhoC 免疫组织化学 |
Expression and correlation of RhoC and TERT protein in human gastric carcinoma |
| |
| QU Yi-kun,LIU Wei-xin,XU Jian,LV Shu-hui. Expression and correlation of RhoC and TERT protein in human gastric carcinoma[J]. Journal Of Tropical Medicine, 2013, 13(5): 634-636,640 |
| |
| Authors: | QU Yi-kun LIU Wei-xin XU Jian LV Shu-hui |
| |
| Affiliation: | (The General Surgery of the First Affiliated Hospital of Jiamusi University, Heiloniang, Jiamusi 154002, China) |
| |
| Abstract: | Objective To investigate the expression of RhoC and TERT protein in human gastric carcinoma and their effects on the growth of gastric carcinoma. Method The expression of RhoC and TERT protein in paraffin-embedded gastric carcinoma was examined by immunohistochemical staining method. Results Samples from 105 cases of gastric carcinoma were examined. The expression rate of RhoC and TERT protein was associated with invasion depth, histological type, clinical stage and lymph node metastases （P〈0.01）. The expression of RhoC was significant correlated with TERT （P〈0.01）. Conclusion RhoC and TERT may have a synergistic action in the progression of gastric carcinoma. |
| |
| Keywords: | gastric carcinoma RhoC immunohistochemistry |
| 本文献已被 维普 万方数据 等数据库收录！ |
|
