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多酚化合物抗菌活性的最新进展
引用本文:柯春林,王娣,谢海伟,汪张贵,吕超田,邓源喜.多酚化合物抗菌活性的最新进展[J].食品工业科技,2012,33(17):405-408.
作者姓名:柯春林  王娣  谢海伟  汪张贵  吕超田  邓源喜
作者单位:蚌埠学院生物与食品工程系,安徽蚌埠,233030
基金项目:安徽省高等学校省级自然科学基金项目(KJ2012B094);蚌埠学院博士科研启动基金项目
摘    要:多酚是高等植物的次级代谢产物,对人类健康有着潜在的作用,具有抗氧化、抗过敏、抗炎、抗癌、抗高血压和抗菌等多种生物活性。本文主要报道了多酚化合物的抗细菌和抗真菌活性,讨论了其作用机制及其结构与功能的关系。此外,考虑到目前微生物耐药性已成为全球日益关注的问题,本文也对多酚化合物协同抗生素的抗菌作用进行了讨论。

关 键 词:多酚化合物  抗菌活性  抗菌机制

Research progress in antibacterial activity of polyphenol compounds
KE Chun-lin,WANG Di,XIE Hai-wei,WANG Zhang-gui,LV Chao-tian,DENG Yuan-xi.Research progress in antibacterial activity of polyphenol compounds[J].Science and Technology of Food Industry,2012,33(17):405-408.
Authors:KE Chun-lin  WANG Di  XIE Hai-wei  WANG Zhang-gui  LV Chao-tian  DENG Yuan-xi
Affiliation:(Department of Biotechnology and Food Engineering,Bengbu College,Bengbu 233030,China)
Abstract:Polyphenols are secondary metabolites produced by higher plants,which have potential healthy properties on human organism,mainly as antioxidants,anti-allergic,anti-inflammatory,anticancer,antihypertensive,and antimicrobial agents.In the present review the antibacterial and antifungal activities of the most active polyphenol classes are reported,highlighting,where investigated,the mechanisms of action and the structure-activity relationship.Moreover,considering that the microbial resistance has become an increasing global problem,the synergistic effect of polyphenols in combination with conventional antimicrobial agents against clinical multidrug-resistant microorganisms was discussed.
Keywords:polyphenol compounds  antimicrobial activity  antimicrobial mechanism
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