颅底脊索瘤的临床研究进展

颅底脊索瘤是一种原发低度恶性肿瘤,具有局部侵袭特性和高复发率,预后较差。作者结合文献对颅底脊索瘤的流行病学、临床表现、影像学特征及组织病理学等方面进行了精要回顾,对脊索瘤的临床分型及分期、治疗原则及生存与预后相关的因素等做了详细的综述,认为目前国内外对颅底脊索瘤的诸多方面的研究仍存在很大的分歧,需要进一步明确。

Recent advances in clinical of skull base chordoma

Skull base chordoma is a rare low-grade malignant tumor.Due to its critical location,local aggressive nature,and high recurrence,skull base chordoma is still a challenge to clinicians.In this review,we summarize the epidemiology,clinical manifestations,imaging features and histopathology of skull base chordoma.Moreover,through the detailed review on this tumor’s clinical type and stage,management,and prognostic factors,we find out that many aspects of the skull base chordoma,at home and abroad,are still significant differences.Further studies are necessary to evaluate these differences of skull base chordoma.