头孢噻肟与亚胺培南西司他丁钠治疗新生儿败血症的效果比较研究

目的：对头孢噻肟与亚胺培南西司他丁钠治疗新生儿败血症的效果进行分析，为临床治疗提供参考。方法方便选取该院2011年2月—2015年2月期间诊治的120例新生儿败血症患儿进行分析，比较头孢噻肟与亚胺培南西司他丁钠的治疗效果。结果头孢噻肟治疗组和亚胺培南西司他丁钠治疗组患者血培养病原菌的种类无统计学差异性(P>0.05)；头孢噻肟的有效率(86.7%)明显低于亚胺培南西司他丁钠的有效率(96.7%)(P<0.05)，但二者不良反应差异无统计学意义(P>0.05)。结论头孢噻肟与亚胺培南西司他丁钠均对新生儿败血症有一定疗效，但后者效果更佳。

Comparative Research on Effect of Cefotaxime and Imipenem and Cilastatin Sodium in Treatment of Neonatal Septicemia

Objective To analyze the effect of cefotaxime and imipenem and cilastatin sodium in treatment of neonatal sep-ticemia and provide reference for the clinical treatment. Methods 120 cases of children with septicemia diagnosed and treated in our hospital from February 2011 to February 2015 were analyzed, and the treatment effects of cefotaxime and imipenem and cilastatin sodium were compared. Results There was no statistical difference in the type of pathogen isolated from blood between the cefotaxime treatment group and the imipenem and cilastatin sodium group, P>0.05, the effective rate of cefotaxime was obviously lower than that of imipenem and cilastatin sodium, (86.7%vs 96.7%), P<0.05, but there was no statistical difference in the adverse reaction between them, P>0.05. Conclusion Cefotaxime and imipenem and cilastatin sodium in treatment of neonatal septicemia has a certain curative effect, but the effect of the latter is better.